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Found 14 clinical trials
An Enhanced Package of Care to Reduce Reduce Mortality in Advanced HIV Disease (ENCORE)

A community-based Phase III, cluster randomized trial that seeks to determine the 24 week survival with retention in care of point of care CD4 testing with visitect and an enhanced package of screening and prophylaxis for opportunistic infections among patients with advanced HIV disease.

  • 0 views
  • 04 Oct, 2022
  • 1 location
Dexamethasone for Cerebral Toxoplasmosis

Toxoplasma gondii infects over one third of the global human population. Cerebral toxoplasmosis is the most common opportunistic infection in HIV patients resulting in up to 50% of mortality

  • 0 views
  • 15 May, 2021
  • 1 location
RAPA-201 T Cell Therapy for Relapsed, Refractory Multiple Myeloma

RAPA-201-RRMM is an open-label, single-arm, non-randomized multicenter phase II study of RAPA-201 autologous T cells in adults with relapsed, refractory multiple myeloma who have received at least three (3) prior lines.

  • 1 views
  • 25 Mar, 2022
  • 1 location
Immediate ART in Subjects With Opportunistic Diseases

therapy once the opportunistic infection is under control at the discretion of infectious disease specialist.

antiretroviral agents
hiv diagnosis
opportunistic infection
HIV Infection
antiretroviral therapy
  • 9 views
  • 22 Mar, 2022
  • 1 location
Treatment of CMV Infections With Viral-Specific T Cells Against CMV in Pediatric and Adult Immunocompromised Patients or Recipients of Allogeneic Stem Cell Transplantation

The present trial will consist of the treatment of 20 pediatric and adult Hematopoietic Stem Cell Transplantation (HSCT) recipients or immunocompromised participants diagnosed with opportunistic Cytomegalovirus (CMV) infections with virus-specific, antigen-selected T-cells. CMV-specific T-cells will be isolated from donor leukapheresis products using the CliniMACS® Prodigy. Prior studies on transfer of …

foscarnet
antiviral therapy
dhpg
stem cell transplantation
colitis
  • 41 views
  • 23 Oct, 2022
  • 1 location
T Cell Therapy of Opportunistic Cytomegalovirus Infection

The purpose of this study is to determine if a specific type of cell-based immunotherapy, using T-cells from a donor that are specific against cytomegalovirus (CMV) is feasible to treat infections by CMV. Adoptive T-cell therapy is an investigational (experimental) therapy that works by using the blood of a donor …

foscarnet
antiviral therapy
allogeneic hematopoietic stem cell transplant
cell therapy
dhpg
  • 81 views
  • 04 Oct, 2022
  • 1 location
A Study of Ustekinumab in Pediatric Participants (U-POPS) With Juvenile Psoriatic Arthritis or Psoriasis (U-POPS)

The purpose of the study is to evaluate pharmacokinetics (PK) of ustekinumab in juvenile psoriatic arthritis (jPsA) and pediatric psoriasis (PsO).

ustekinumab
arthritis
rheumatism
  • 0 views
  • 10 Apr, 2023
  • 7 locations
Comprehensive Diagnosis and Treatment Strategy for Opportunistic Fungal Infections in AIDS Patients

Opportunistic fungal infection is the most common opportunistic infection in AIDS patients, with the high mortality and recurrence rate due to the lack of standardized comprehensive diagnosis

  • 0 views
  • 24 Dec, 2021
  • 1 location
An Observational Study to Evaluate Safety and Efficacy of Remsima™ in Patients With Ankylosing Spondylitis

An Observational, Prospective Cohort Study to Evaluate Safety and Efficacy of RemsimaTM in Patients with Ankylosing Spondylitis

  • 31 views
  • 22 Jan, 2022
  • 1 location
Clinical and Immunologic Monitoring of Patients With Known or Suspected HIV Infection

This study will investigate HIV infection and associated conditions by monitoring infected patients. The study will also serve as a means for recruiting HIV-infected individuals to NIAIDs ongoing clinical and laboratory studies and supporting the institute s infectious disease training program by providing Infectious Disease fellows with ongoing training in …

enzyme-linked immunosorbent assay
western blot
HIV Infection
HIV Vaccine
  • 26 views
  • 11 Apr, 2023
  • 1 location