Found 15 clinical trials
Dexamethasone for Cerebral Toxoplasmosis
Toxoplasma gondii infects over one third of the global human population. Cerebral toxoplasmosis is the most common opportunistic infection in HIV patients resulting in up to 50% of mortality
- 0 views
- 15 May, 2021
- 1 location
Assessment of Group Peer Support to Children With HIV in Vietnam
This project aims to assess the effect of group peer support to children with HIV in relation to adherence, virological treatment failure as well as physical development. A randomised controlled trial (RCT) will be used where HIV+ children on antiretroviral treatment (ARV) and their caretakers are randomized into either enhanced …
- 0 views
- 26 Feb, 2021
- 1 location
Immediate ART in Subjects With Opportunistic Diseases
therapy once the opportunistic infection is under control at the discretion of infectious disease specialist.
- 0 views
- 21 Jul, 2021
- 1 location
Treatment of Cytomegalovirus (CMV) Infections With Viral-Specific T Cells
The present trial will consist of the treatment of 20 pediatric and adult Hematopoietic Stem Cell Transplantation (HSCT) recipients or immunocompromised participants diagnosed with opportunistic Cytomegalovirus (CMV) infections with virus-specific, antigen-selected T-cells. CMV-specific T-cells will be isolated from donor leukapheresis products using the CliniMACS Prodigy. Prior studies on transfer of …
- 41 views
- 29 Jan, 2021
- 1 location
T Cell Therapy of Opportunistic Cytomegalovirus Infection
The purpose of this study is to determine if a specific type of cell-based immunotherapy, using T-cells from a donor that are specific against cytomegalovirus (CMV) is feasible to treat infections by CMV. Adoptive T-cell therapy is an investigational (experimental) therapy that works by using the blood of a donor …
- 77 views
- 28 Apr, 2021
- 2 locations
LLL Phototherapy in Oral Lesions Resulting From Anti-neoplastic Prevention
referring to oral mucositis (OM), radiodermatitis, osteonecrosis of the jaws (ONJ), hyposalivation and xerostomia, dysgeusia, pain, oral candidiasis (opportunistic infection), trismus, quality of life, oral
- 0 views
- 05 Aug, 2021
- 1 location
Point-of Care Ultrasound for Patients With HIV
Rationale: Point-of-care ultrasound (POCUS) is increasingly used by various specialists in the Netherlands, but its role in managing patients with HIV is unclear. In settings endemic for tuberculosis, Fast Assessment with Sonography for HIV/Tuberculosis (FASH) has proven its value to detect extrapulmonary tuberculosis in patients with HIV. However, there is …
- 0 views
- 24 Jan, 2021
- 1 location
Early Community Client-LED ART Delivery in Nakivale Refugee Settlement
To pilot early community client-led ART (anti-retroviral therapy) delivery (CCLAD) in Nakivale Refugee Settlement in Uganda and assess the feasibility and acceptability of this intervention in this setting.
- 0 views
- 13 Feb, 2021
- 1 location
Antigen-specific Cytotoxic T Cells in the Treatment of Opportunistic Infections
Epstein Barr Virus (EBV) or Cytomegalovirus (CMV) infection results in significant morbidity and mortality in hematopoietic stem cell transplantation (HSCT) patients. HSCT patients often face opportunistic infections due to the immunosuppressive state during transplantation. Antimicrobial drugs are usually used for prophylactic purposes and for treatment after early detectable infections. Unfortunately, …
- 22 views
- 23 Jan, 2021
- 1 location
An Observational Study to Evaluate Safety and Efficacy of Remsima in Patients With Ankylosing Spondylitis
An Observational, Prospective Cohort Study to Evaluate Safety and Efficacy of RemsimaTM in Patients with Ankylosing Spondylitis
- 31 views
- 22 Jan, 2021
- 1 location
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