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Found 104 clinical trials
Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification

Methadone is a very long-acting opiate very difficult to detox from. In Spain there are a lot of methadone dependent people in the aftermath of the heroin epidemic of the 1980s. Many have been dependent for more than 15 years and a number of them have a relatively stable life …

opioid
opioid withdrawal
methadone maintenance
methadone
detoxification
  • 148 views
  • 07 Oct, 2022
  • 1 location
Does ESP Block Reduce Pain and Opiates Consumption After Surgery

The patients will be randomly assigned to standard therapy or standard therapy+ESP nerve block. After surgery pain level and narcotic consumption will be measured, and vital signs and side effects will bo monitored for up to 72 hours. 6 months after surgery a phone interview will be conducted to asses …

dexamethasone
chronic pain
anesthetic drug
Accepts healthy volunteers
opiates
  • 0 views
  • 04 Oct, 2022
  • 1 location
KAP for Depression in Abstinent Opioid Users (KReDO)

opioid addiction who have not abused opioids in at least 3 months. Participants will receive ketamine through intramuscular injection along with psychotherapy weekly for 8 weeks. Participation for

  • 10 views
  • 04 Oct, 2022
  • 1 location
Efficacy of Spinal Manipulation Therapy or Mindfulness-based Reduction Therapy on Patients With Chronic Low Back Pain

Chronic Pain Management (CPM) has increasingly utilized long-term opioid analgesic therapy, a change associated with increased opioid abuse (a greater exposure in vulnerable individuals), non

  • 0 views
  • 17 Feb, 2021
  • 2 locations
Detecting Drugs of Abuse Via Exhaled Breath Samples Using Differential Mobility Spectrometry

This Phase II STTR program consists of two major goals within the overarching goal of developing and validating a proprietary device (BID2) for marijuana and opioid detection in breath samples.

opioid
drugs of abuse
body mass index
Accepts healthy volunteers
diabetes
  • 0 views
  • 11 Jul, 2022
  • 1 location
A Pilot Study Investigating the nCAP Signal Relief Patch in Subjects Undergoing Primary Hip or Knee Replacement Surgery

Opioid addiction in post-operative patients is recognized but not fully understood; therefore, in order to address this growing crisis, it is essential to explore alternative approaches to

  • 0 views
  • 28 May, 2022
  • 1 location
Addressing Opioid Use Disorder With an External Multimodal Neuromodulation Device: Clinical Evaluation of DuoTherm for Opioid-Sparing in Chronic Low Back Pain

Evaluate opioid use and pain change in chronic Low Back Pain with DuoTherm Compared to Active Control

opioid
opioid use
  • 0 views
  • 11 Oct, 2022
  • 2 locations
Brain Dopaminergic Signaling in Opioid Use Disorders

Background The chemical messenger dopamine carries signals between brain cells. It may affect addiction. Heavy use of pain medicines called opioids may decrease the amount of dopamine available to the brain. Researchers want to study if decreased dopamine decreases self-control and increases impulsiveness. Objective To learn more about how opiate …

opioid
opioid agonist
addiction
methadone
medication treatment
  • 587 views
  • 04 Oct, 2022
  • 1 location
SIRI Checklist: An Integrated Hospital Model to Optimize HIV Prevention in Persons Who Inject Drugs (SHAPE)

The purpose of this study is to develop and test a serious injection-related injections (SIRI) checklist aimed at increasing evidence-based treatment for rural people who use drugs (PWUD) including innovative, long-acting injectable agents. The central hypothesis is that hospital-based care models can successfully engage rural and Southern (PWUD) in effective …

  • 0 views
  • 27 Oct, 2022
  • 1 location
Young Houston Emergency Opioid Engagement System (YHEROES)

The Houston Emergency Response Opioid Engagement System for Youths and Adolescents (Young HEROES) is a community-based research program integrating assertive outreach, medication for opioid use disorder (MOUD), behavioral counseling, and peer recovery support. The objective is to compare differences in engagement and retention in treatment for individuals with opioid use …

opioid
medication treatment
drug screen
drug dependence
toxicology screen
  • 0 views
  • 30 May, 2022
  • 1 location