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Found 104 clinical trials
Integrating Support Persons Into Recovery

INtegrated Support Persons Into Recovery (INSPIRE) is a 4-year research project that tests whether integrating a patient's support person into a patient's treatment with Buprenorphine/Naloxone can improve outcomes. The study will examine whether a counseling program called CRAFT for a support person, such as a family member, spouse or friend, …

substance use
buprenorphine
  • 10 views
  • 09 Jul, 2021
  • 3 locations
Medication Adherence Therapy - Psychosocial Leverage Using a Treatment Significant Other (MAT-PLUS)

) patients with OUD. Adult patients ages 18+ who receive an initial dose of XRNTX during an index episode of inpatient/residential/detox treatment for opioid addiction at a public-sector community treatment

opioid
opioid use
narcotic use
addiction
detox
  • 66 views
  • 17 Oct, 2022
  • 1 location
EA for Protracted Withdrawal of OUD

Opioid use disorder (OUD) the most harmful of all the illicit drugs is a serious substance-related disorder resulting from abuse or misuse of opioids. Huge number of patients are addictive to opioid and evidences show that patients with OUD have high rates of infectious diseases.The "World Drug Report 2020" has …

opioid
opioid use
addiction
detoxification
depression
  • 4 views
  • 24 Jul, 2021
  • 1 location
Buprenorphine Treatment at Syringe Exchanges to Reduce Opioid Misuse and HIV Risk (O-BMT)

This trial will recruit syringe exchange participants with opioid use disorder in New York City and test whether starting buprenorphine treatment at the syringe exchange program is more effective than referral to a community health center for buprenorphine treatment.

narcotic use
opioid use disorder
buprenorphine
  • 22 views
  • 20 Oct, 2022
  • 3 locations
An Innovative Intervention for OUD Treatment

The Bridge Device (BD) is a neuromodulator medical device that has been cleared by the FDA for Opioid Use Disorder (OUD) treatment. Importantly, medical devices reviewed by the FDA are cleared (based on safety) rather than approved (based on efficacy), which means the BD did not need to demonstrate efficacy …

opioid
opioid use
morphine
Accepts healthy volunteers
opioid use disorder
  • 15 views
  • 22 Dec, 2021
  • 1 location
Pharmacologically-based Strategies for Opioid Substitution Therapy During Pregnancy

This study will evaluate maternal tolerance to several BUP dose reduction strategies.

opioid
substitution therapy
illicit drugs
buprenorphine
drugs of abuse
  • 80 views
  • 05 Jul, 2022
  • 2 locations
Stagewise Implementation-To-Target- Medications for Addiction Treatment (SITT-MAT) (SITT-MAT)

The purpose of this study is to expand access to medications for opioid use disorder (MOUD) in specialty addiction programs in Washington State. Sixty-four addiction treatment programs will participate in an adaptive implementation strategy trial that uses a stagewise implementation-to-target (stepped "care" type) approach whereby organizations engage in increasingly intensive …

  • 0 views
  • 07 Oct, 2022
  • 1 location
Opioid/Benzodiazepine Polydrug Abuse: Aim 3 (MAP)

In this study, the investigators will measure affective, neurocognitive and behavioral outcomes related to chronic use of opioids and benzodiazepines (screening phase), and in response to the administration of the opioid morphine, the benzodiazepine alprazolam, morphine then alprazolam, alprazolam then morphine, morphine+alprazolam simultaneously, and placebo (laboratory pharmacology experiment). The latter …

opioid
opioid use
morphine
substance use
opioid use disorder
  • 0 views
  • 11 Jul, 2022
  • 1 location
Substance Use Treatment and Recovery Team (START)

This study is a multi-site, randomized pragmatic trial being conducted at three diverse sites. The study, called the Substance Use Treatment and Recovery Team (START), will evaluate whether a collaborative care team increases the use of two interventions-medication for opioid use disorder (MOUD), and opioid use disorder (OUD) focused discharge …

opioid
opioid use
addiction
substance use
opioid use disorder
  • 41 views
  • 04 Oct, 2022
  • 3 locations
Healthy Opioid Prescription Engagement

This study is a randomized controlled trial across 14 community pharmacies to test the efficacy of the Brief Intervention-Medication Therapy Management intervention (BI-MTM). The establishment of the BI-MTM model will result in a major impact for addressing the opioid epidemic, preventing opioid use disorder and overdose, and safeguarding patient health …

opioid
opioid use
toxicology screen
opioid use disorder
  • 0 views
  • 27 Dec, 2021
  • 1 location