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Found 954 clinical trials
Sound Processing Changes in Babies With Opioid Exposure

The purpose of this study is to identify problems with interpreting sounds in babies that have been exposed to opioids prior to birth. Being able to identify these issues in infancy may allow us to find children who may have problems with language learning later in life so that we …

prenatal
opioid
toxicology screen
  • 0 views
  • 05 Mar, 2022
  • 1 location
Does Medical Cannabis Reduce Opioid Use in Adults With Pain (ReLeaf-E)

The study will examine how medical cannabis use affects opioid analgesic use. This landmark study will be among the first to examine the effect of medical cannabis with different THC/CBD content

substance use
opioid
cannabis use
neuralgia
analgesics
  • 0 views
  • 25 Mar, 2022
  • 1 location
Maternal Opioid Treatment: Human Experimental Research - Data Yield Appropriate Decisions (MOTHER DYAD)

This study will compare medically-supervised withdrawal (MSW, 'detoxification') to opioid agonist treatment (OAT, 'maintenance') with buprenorphine for pregnant women with opioid use disorder in

opioid agonist
opioid use
detoxification
opioid
urine drug screen
  • 68 views
  • 23 Apr, 2022
  • 3 locations
Postpartum Pain Experience and Attitudes About Opioid Prescribing

interventions aimed at reducing opioid use, and the biases which may contribute disparities in this setting.

  • 0 views
  • 22 Mar, 2022
  • 1 location
MOM NEST Study: Maternal Opioid Medication: Naltrexone Efficacy Study

This is a multi-center prospective comparative cohort study examining the safety, efficacy, pharmacokinetics, and pharmacogenomics of naltrexone for pregnant women with opioid use disorder

prenatal
opioid use
opioid
buprenorphine
buprenorphine/naloxone
  • 68 views
  • 18 Aug, 2021
  • 2 locations
The Association of Microbiome Patterns With Chronic Opioid Use

The United States is in the midst of an opioid epidemic, with the number of opioid-related deaths having risen six-fold since 1999. Chronic pain imposes a tremendous economic burden of up to US

central sensitization
opioid
chronic pain
  • 0 views
  • 27 Apr, 2022
  • 1 location
Precision Opioid Care After Cesarean Delivery (PRECISE-CD) (PRECISE-CD)

The purpose of this research is to study serious clinical problems from both surgical pain and oxycodone and opioid use in women having a Cesarean Delivery to improve the safety and efficacy of

  • 0 views
  • 28 Apr, 2022
  • 1 location
Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes (Mother/BabyOUD)

poor response to opioid substitution and infants at risk of significant neonatal abstinence syndrome (NAS).

Accepts healthy volunteers
  • 28 views
  • 24 Mar, 2022
  • 1 location
Linking Epigenomics With Prescription Opioid Abuse and High Impact Musculoskeletal Pain

Genetic variability from epigenetic modification of genes related to pain physiology and opioid pharmacodynamics may influence susceptibility to high-impact chronic musculoskeletal pain, opioid

addiction
opioid
opioid dependence
drug abuse
analgesics
  • 242 views
  • 29 Mar, 2021
  • 2 locations
Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients

This study is designed to find behavioral and neurophysiological correlates of pain avoidance behavior among chronic pain patients, controlling for risk for opioid use disorder. Further, traits

opioid
chronic pain
anxiety
  • 0 views
  • 23 Mar, 2022
  • 1 location