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Found 905 clinical trials
Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

This is a pilot study to evaluate the safety and efficacy of deep brain stimulation (DBS) of the nucleus accumbens (NAc) as adjunctive treatment for treatment-refractory opioid use disorder

  • 0 views
  • 14 Mar, 2022
  • 1 location
Mindful Body Awareness With Medication Treatment for Opioid Use Disorder

The national opioid epidemic requires development of real-world evidence-based treatments for opioid use disorder, including adjuncts to Medication Treatment (MT). Interventions are needed that

  • 172 views
  • 07 Oct, 2022
  • 4 locations
Opioid Free Anesthesia Versus Opioid Based Anesthesia for Improvement of the Surgical Field Condition in Elderly Patients Undergoing Arthroscopic Shoulder Surgery. A Randomized Comparative Study

increased risk complications as myocardial infarction, stroke and delirium. Opioid free anesthesia is a technique with no opioids administered intraoperatively through either systemic, neuraxial, or

Accepts healthy volunteers
  • 0 views
  • 20 Oct, 2022
  • 1 location
Long-acting Buprenorphine vs. Naltrexone Opioid Treatments in CJS-involved Adults

This study seeks to compare the effectiveness of two medications used to treat opioid use disorder, extended-release buprenorphine (XR-B) vs. extended-release naltrexone (XR-NTX), among adults

  • 15 views
  • 24 Mar, 2022
  • 2 locations
The Effect of Buprenorphine Continuation for Patients With Opioid Use Disorder

inadequate pain control necessitating opioid escalation when buprenorphine is continued. Preliminary clinical observations support buprenorphine continuation at low analgesic doses (8mg) as it adequately

  • 0 views
  • 03 May, 2022
  • 1 location
Pilot Study of a Multi-System Analysis of Opioid Receptor Binding

This study in up to 20 healthy subjects (including 10 females and 10 males) will use [11C]carfentanil whole-body PET imaging to examine the CNS and broader systemic opioid binding and its

Accepts healthy volunteers
  • 0 views
  • 23 Oct, 2022
  • 1 location
Therapy and Peer Support for Patients Taking Medication for Opioid Use Disorder

Current clinical guidelines for medication assisted treatment (MAT) of opioid use disorder (OUD) recommend that treatment include a psychosocial component to help address psychological factors

addiction
buprenorphine
narcotic use
  • 52 views
  • 26 Jan, 2021
  • 4 locations
Coordinating Opioid Use Treatment Through Medical Management With Infection Treatment (Project COMMIT)

This study seeks to test a new model of care (ID/LAB) in which opioid use disorder (OUD) is managed by infectious disease (ID) specialists and hospitalists concurrent with management of the OUD

  • 0 views
  • 26 Nov, 2021
  • 3 locations
Use of SVS Device to Improve Outcomes for Neonatal Opioid Withdrawal Syndrome.

Maternal use and addiction to opioids has resulted in an unprecedented rise in drug withdrawal complications in newborns known as neonatal opioid withdrawal syndrome (NOWS), also referred to as

  • 4 views
  • 15 Dec, 2021
  • 1 location
Oxytocin to Reduce Stress-induced Craving in Individuals With Opioid Use Disorder (OSCO)

rise in opioid use, there is still a crucial need for developing effective pharmacological treatments that target and integrate the complexity of this disease. The long term goal of this project is to

substance use
buprenorphine
narcotic use
opiates
oxytocin
  • 90 views
  • 18 Oct, 2022
  • 1 location