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Found 1037 clinical trials
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A Pilot Study of Ultra Rapid Opioid Rotation and Titration of Oxymorphone

This project will explore the safety and feasibility of performing a successful intravenous patient controlled analgesia (IV PCA) Oxymorphone titration and conversion to oral ER Oxymorphone (extended release or OPANA ER) in the outpatient setting.

opioid
morphine
analgesia
cancer
oxycodone
  • 302 views
  • 08 Nov, 2020
  • 1 location
None
Long Acting Naltrexone for Opioid Addiction: Focus on Sustained Abstinence and Recovery

This study is designed as an open-label evaluation of how treatment with XR-NTX may influence the quality and speed of recovery of opioid dependent individuals - in a context of a naturalistic

  • 12 views
  • 23 Jan, 2021
  • 1 location
None
Coordinating Opioid Use Treatment Through Medical Management With Infection Treatment (Project COMMIT)

This study seeks to test a new model of care (ID/LAB) in which opioid use disorder (OUD) is managed by infectious disease (ID) specialists and hospitalists concurrent with management of the OUD

  • 0 views
  • 26 Nov, 2021
  • 3 locations
None
Cannabidiol Use to Reduce Cravings in Individuals With Opioid Use Disorder on Buprenorphine

The purpose of this week-long study is to determine the impact of cannabidiol on cue-induced cravings among individuals with opioid use disorder who are stable on sublingual buprenorphine

  • 0 views
  • 03 Feb, 2021
None
Therapy and Peer Support for Patients Taking Medication for Opioid Use Disorder

Current clinical guidelines for medication assisted treatment (MAT) of opioid use disorder (OUD) recommend that treatment include a psychosocial component to help address psychological factors

buprenorphine
narcotic use
addiction
  • 45 views
  • 26 Jan, 2021
  • 4 locations
None
Extended-Release Buprenorphine vs. Sublingual Buprenorphine for the Treatment of Opioid Use Disorder

The study is 12-week, randomized, open-label study comparing injectable extended-release buprenorphine (Sublocade) to standard therapy (sublingual buprenorphine), to see if Sublocade will be more helpful in treating opiate use for individuals testing positive for fentanyl and related high potency drugs (HPSO). Those receiving Sublocade will have it administered monthly and …

  • 12 views
  • 07 Aug, 2021
  • 1 location
None
Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD)

The purpose of this clinical trial is to investigate Low Intensity Focused Ultrasound (LIFU) using the Exablate Model 4000 Type 2.0/2.1 as an adjunctive neuromodulatory treatment for OUD (Opioid

  • 8 views
  • 29 Aug, 2021
  • 1 location
None
Connection Navigation Engagement in Care and Treatment for Opioid Use Disorder

The overarching goal of the study is to develop, pilot, and evaluate an intervention that aims to retain patients who initiate buprenorphine at Denver Health in ongoing treatment for opioid use

  • 0 views
  • 12 Apr, 2021
  • 1 location
None
Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation

This study is a prospective randomized trial examining the effect of topically combined antifibrinolytics (Tranexamic acid) with local anesthetics in all electively created surgical wound beds in hand surgery to provide long term pain relief and decrease the use of postoperative narcotics.

  • 0 views
  • 02 Apr, 2021
  • 1 location
None
Intervention Development and Pilot Study to Prevent Untreated Native Hawaiian and Pacific Islander Opioid Use Disorder

This study will design and pilot/feasibility test a culturally grounded intervention to increase the treatment seeking of Pacific Islanders with opioid use disorders in formal services.

  • 0 views
  • 02 Jun, 2021
  • 1 location