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Found 957 clinical trials
Community Opioid Innovation Network (JCOIN): TCU Clinical Research Center (JCOIN_TCU)

Opioid-Treatment Linkage Model (O-TLM) protocol. The O-TLM is focused on best practices for improving screening, identifying and linking to MOUD providers, reducing stigma, and addressing other important

  • 0 views
  • 14 Mar, 2022
  • 1 location
Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

This is a pilot study to evaluate the safety and efficacy of deep brain stimulation (DBS) of the nucleus accumbens (NAc) as adjunctive treatment for treatment-refractory opioid use disorder

  • 0 views
  • 14 Mar, 2022
  • 1 location
Tailoring a Mindful Intervention to Enhance Opioid Treatment

The main aim of this study is to better understand whether yoga can be blended with mindfulness as an additional intervention for people receiving medication assisted treatment at a Hartford-based community agency. If this program is acceptable to participants, then additional studies can allow us to determine its impact on …

  • 0 views
  • 16 May, 2021
  • 1 location
A Study of Oral Ibogaine in Opioid Withdrawal

healthy volunteers, followed by a randomized, double-blind, placebo-controlled proof of concept stage to demonstrate the efficacy, safety and tolerability of the selected dose in opioid-dependent patients

  • 0 views
  • 12 Sep, 2021
  • 1 location
Frontoparietal Synchronization to Modulate Drug Craving in Opioid Use Disorder (FPS_Opioid)

Opioid use disorder (OUD) is among the costliest and deadliest substance use disorders (SUDs) in the US and world-wide. Opioids were involved in 42,249 deaths in the US in 2016, which were more

  • 183 views
  • 12 May, 2022
  • 1 location
Long-acting Buprenorphine vs. Naltrexone Opioid Treatments in CJS-involved Adults

This study seeks to compare the effectiveness of two medications used to treat opioid use disorder, extended-release buprenorphine (XR-B) vs. extended-release naltrexone (XR-NTX), among adults

  • 15 views
  • 24 Mar, 2022
  • 2 locations
Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation

This study is a prospective randomized trial examining the effect of topically combined antifibrinolytics (Tranexamic acid) with local anesthetics in all electively created surgical wound beds in hand surgery to provide long term pain relief and decrease the use of postoperative narcotics.

Accepts healthy volunteers
  • 0 views
  • 24 Mar, 2022
  • 1 location
Heterodyned Whole-Body Vibration in Treatment of Opioid Withdrawal-Induced Anxiety

In this randomized, double-blind, controlled, parallel group study (conducted over 12-months), enrollment is expected of up to 60 subjects (30 men and 30 women) ages 18+ who are currently going through withdrawal of OUD and being treated at local substance abuse clinics. The study visits will include screening, baseline, Weeks …

  • 0 views
  • 16 Mar, 2022
  • 1 location
A Mobile Executive Functioning Intervention for Momentary Craving in Opioid Use Disorders

Even when treated with methadone or buprenorphine maintenance, many people with opioid use disorder (OUD) continue to experience craving. Among both users of heroin and users of prescription

  • 0 views
  • 28 Oct, 2021
  • 1 location
Effects of Peripherally Acting µ-opioid Receptor Antagonists on Acute Pancreatitis

This study will investigate the effect of peripheral acting opioid antagonist (PAMORA) on the disease course of patients with acute inflammation of the pancreas (acute pancreatitis). The study

  • 0 views
  • 13 Dec, 2021
  • 4 locations