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Found 1031 clinical trials
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Response to Relapse in Office-Based Opioid Treatment Trial

In a sample of individuals with co-occurring OUD and mental disorders, the investigators plan to test two medications for opioid use disorder (MOUD) treatment protocols that involve differing

  • 1 views
  • 24 Jan, 2021
None
Mindful Body Awareness With Medication Treatment for Opioid Use Disorder

The national opioid epidemic requires development of real-world evidence-based treatments for opioid use disorder, including adjuncts to Medication Treatment (MT). Interventions are needed that

  • 46 views
  • 17 Nov, 2021
  • 5 locations
None
Tailoring a Mindful Intervention to Enhance Opioid Treatment

The main aim of this study is to better understand whether yoga can be blended with mindfulness as an additional intervention for people receiving medication assisted treatment at a Hartford-based community agency. If this program is acceptable to participants, then additional studies can allow us to determine its impact on …

  • 0 views
  • 16 May, 2021
  • 1 location
None
Neurobehavioral Mechanisms of Choice in Opioid Use Disorder

The objective of this protocol is to use probabilistic reinforcement learning choice tasks and magnetic resonance neuroimaging to demonstrate the impact of problematic opioid use and opioid

oxycodone
narcotic use
opioid withdrawal
  • 157 views
  • 24 Nov, 2021
  • 1 location
None
Effects of Peripherally Acting -opioid Receptor Antagonists on Acute Pancreatitis

This study will investigate the effect of peripheral acting opioid antagonist (PAMORA) on the disease course of patients with acute inflammation of the pancreas (acute pancreatitis). The study

  • 0 views
  • 20 Jul, 2021
  • 4 locations
None
Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation

The purpose of this study is to compare the efficacy of subcutaneous versus oral mu-opioid receptor antagonist therapy in opioid induced constipation that is refractory to other bowel regimens

  • 11 views
  • 06 Mar, 2021
  • 1 location
None
Disclosure Intervention for People in Recovery From Opioid Use Disorder

Many people with substance use disorders struggle with decisions regarding whether to disclose to others that they have a history of substance use and/or are in recovery. Yet, these decisions are important because disclosures can lead to reactions from others that harm or help recovery. For example, stigmatizing responses can …

  • 0 views
  • 29 Oct, 2021
  • 1 location
None
A Study of Oral Ibogaine in Opioid Withdrawal

healthy volunteers, followed by a randomized, double-blind, placebo-controlled proof of concept stage to demonstrate the efficacy, safety and tolerability of the selected dose in opioid-dependent patients

  • 0 views
  • 12 Sep, 2021
  • 1 location
None
A Pilot Study of Ultra Rapid Opioid Rotation and Titration of Oxymorphone

This project will explore the safety and feasibility of performing a successful intravenous patient controlled analgesia (IV PCA) Oxymorphone titration and conversion to oral ER Oxymorphone (extended release or OPANA ER) in the outpatient setting.

opioid
morphine
analgesia
oxycodone
cancer
  • 334 views
  • 08 Nov, 2020
  • 1 location
None
Long Acting Naltrexone for Opioid Addiction: Focus on Sustained Abstinence and Recovery

This study is designed as an open-label evaluation of how treatment with XR-NTX may influence the quality and speed of recovery of opioid dependent individuals - in a context of a naturalistic

  • 20 views
  • 23 Jan, 2021
  • 1 location