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Found 958 clinical trials
Ketamine Assisted Psychotherapy for Opioid Use Disorder

This pilot clinical trial aims to assess the preliminary efficacy of ketamine as an adjunct for a mindfulness-based intervention for opioid use disorder.

  • 31 May, 2021
  • 1 location
Clinical Trials of Multivalent Opioid Vaccine Components

Currently, abuse of prescription opioid analgesics and heroin is a serious problem in the U.S. Although several medications, including methadone, buprenorphine, and naltrexone, are available and

  • 05 Jul, 2021
rTMS, Stress and Opioid Use Disorder (TOTS)

Opioid agonist treatments are the gold standard for treating opioid use disorder (OUD). Yet, even effective treatments average only 50% six-month retention. Despite extensive research into

  • 12 May, 2022
  • 1 location
Light Needle for Opioid Use Disorder (OUD)

This randomized-controlled study investigates the effect of adjuvant light needle in the treatment of heroin addicts. One hundred heroin addicts older than 20 years old enrolled from Addiction Treatment Center are randomly allocated to experimental or control group. Subjects in experimental group are treated with light needle on the wrist …

  • 01 May, 2022
  • 1 location
Behavioral Activation for Opioid Use Disorder

for opioid use disorder (OUD) in primary care. Researcher will evaluate the following aims: 1) examine the feasibility of BA for OUD in primary care, 2) examine whether the BA intervention and study

  • 15 May, 2022
  • 1 location
A Comparative Study Between Analgesic Effect of Opioid Free and Opioid Based Anesthesia in Radical Nephrectomy Surgery

at risk (eg, those with sleep apnea), difficulty in voiding, and ileus. These complications may lead to a prolonged hospital stay. High dose opioids can also cause acute opioid tolerance and

Accepts healthy volunteers
  • 27 Apr, 2022
  • 1 location
Neurobehavioral Mechanisms of Choice in Opioid Use Disorder

The objective of this protocol is to use probabilistic reinforcement learning choice tasks and magnetic resonance neuroimaging to demonstrate the impact of problematic opioid use and opioid

narcotic use
opioid withdrawal
  • 21 Mar, 2022
  • 1 location
Mindful Body Awareness With Medication Treatment for Opioid Use Disorder

The national opioid epidemic requires development of real-world evidence-based treatments for opioid use disorder, including adjuncts to Medication Treatment (MT). Interventions are needed that

  • 17 Nov, 2021
  • 5 locations
Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal (PGB-LOF)

A phase II double-blind placebo-controlled parallel group clinical trial that will randomize 90 subjects to investigate whether pregabalin (PGB) combined with Lofexidine (LFX) can reduce opioid

  • 25 Mar, 2022
  • 2 locations
Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation

The purpose of this study is to compare the efficacy of subcutaneous versus oral mu-opioid receptor antagonist therapy in opioid induced constipation that is refractory to other bowel regimens

  • 10 Apr, 2022
  • 1 location