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Found 1032 clinical trials
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A Digital Intervention to Prevent the Initiation of Opioid Misuse in Adolescents in School-based Health Centers

The primary hypothesis of this study is that at 3 months, there will be a higher proportion of intervention participants vs. control participants who report greater risk of harm from misuse of prescription opioids AND heroin/fentanyl.

Accepts healthy volunteers
  • 0 views
  • 13 Nov, 2021
  • 1 location
None
Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

/naloxone microdosing and standard dosing take-home induction regimens at enabling patients to successfully complete the induction regimen, and at retaining patients on opioid agonist therapy. We

  • 14 views
  • 10 Aug, 2021
  • 4 locations
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Emergency Department-Initiated Buprenorphine Validation Network Trial

-initiated buprenorphine (BUP) for patients presenting with opioid use disorder (OUD) who are not receiving medications for opioid use disorder (MOUD). Once implementation is adequately achieved, the sites

  • 425 views
  • 16 Sep, 2021
  • 37 locations
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Project MIMIC (Maximizing Implementation of Motivational Incentives in Clinics)

There is an urgent need for effective treatments for patients with opioid use disorder (OUD). This study will train opioid treatment centers in an evidence-based behavioral treatment called

  • 71 views
  • 08 Dec, 2021
  • 11 locations
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Development of Effective Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries

This study will compare the current standard-of-care pain treatment regimen options that are available to patients who undergo gender-affirming surgery. The purpose of this research is to determine if any of these options are more (versus less) effective than the others to manage surgery related pain, after surgery.

  • 0 views
  • 06 Aug, 2021
  • 1 location
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Implementing Alcohol Misuse SBIRT in a National Cohort of Pediatric Trauma Centers

of AOD use are at elevated risk of opioid misuse. Utilizing a stepped wedge design, a national cohort of 10 pediatric trauma centers will receive the SSL implementation strategy. Data collection for

  • 0 views
  • 02 Jul, 2021
  • 1 location
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Ketorolac Use in Pediatric Patients Undergoing Tonsillectomy

This prospective, randomized, double blinded study is designed to compare the bleeding rates of ketorolac vs. placebo when used for post tonsillectomy pain control in pediatric patients ages 2-18.

  • 0 views
  • 02 Sep, 2021
  • 1 location
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Pain Inflammation and Opioid Craving

The goal of this study is to investigate the association between response to pain and opioid craving in people with opioid use disorder. In this study, adults with opioid use disorder will be

  • 0 views
  • 23 Jul, 2021
  • 1 location
None
Opioid HIV and Immune System

The purpose of this research is to evaluate blood samples from HIV infected and non-HIV infected people opioid and non opioid users to understand how opioid affect the immune responses (body

Accepts healthy volunteers
  • 0 views
  • 23 Nov, 2021
  • 1 location
None
NET Device for Treating Opioid Use Disorder

This prospective, randomized, double-blind, parallel-group, sham-controlled, superiority study will evaluate the effectiveness of the NET device in treating persons with Opioid Use Disorder (OUD

  • 0 views
  • 02 Dec, 2021
  • 1 location