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Found 1038 clinical trials
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Patient Decision Aid for Opioid Use Disorder

The aim of the study is to test the effectiveness of the Patient Decision Aid for Opioid Use Disorder (PtDA-MAT) by conducting a stepped-wedge cluster-randomized trial in CA H&SS (stratified

narcotic use
drug use
substance use
  • 50 views
  • 24 Nov, 2021
  • 1 location
None
Kentucky Women's Justice Community Opioid Innovation Network

This trial will test the effectiveness of delivering medication for opioid use disorder (MOUD) pre-treatment via telehealth, alone and with peer navigation, to increase MOUD initiation and

Accepts healthy volunteers
  • 0 views
  • 25 Oct, 2021
  • 6 locations
None
Effect of Intravenous S-ketamine on Opioid Consumption

Female patients with an American Society of Anesthesia (ASA) physical status I-II, scheduled for elective breast cancer surgery will be included in the study. Subjects will be randomly assigned to one of three groups: the placebo group, the low-dose S-ketamine group, and the high-dose S-ketamine group. The primary outcome is …

  • 0 views
  • 26 Nov, 2021
  • 1 location
None
Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0)

Through CTN-0076-Ot (Clinical Decision Support for Opioid Use Disorders in Medical Settings: Pilot Usability Testing in an EMR (COMPUTE)), our team has iteratively developed and piloted a web

  • 5 views
  • 02 Apr, 2021
  • 1 location
None
Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries

: the Opioid trial or the Non-Opioid trial. If they select the Non-opioid trial, they will have an equal chance of receiving either (a) Ibuprofen OR (b) Ibuprofen and acetaminophen. If they select the

  • 8 views
  • 10 May, 2021
  • 12 locations
None
Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)

The objective of this study is to evaluate the efficacy of a rapid wean intervention compared with a slow-wean intervention in reducing the number of days of opioid treatment from the first dose

  • 0 views
  • 15 Feb, 2021
  • 26 locations
None
Cardiovascular Protection Conservative Effects of Esketamine Versus -opioid Receptor Agonists in General Anesthesia

including intra- and postoperative pain. The -opioid receptor agonists induce analgesic effect via inhibition of the transduction and the transmission of pain signals, by suppression of the release of CGRP

  • 0 views
  • 26 Mar, 2021
  • 1 location
None
Optimizing Retention Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

This is a two phase study investigating combinations of pharmacological and behavioral interventions to optimize the treatment of Opioid Use Disorder (OUD). The Retention Phase will assess

  • 12 views
  • 25 Nov, 2021
  • 20 locations
None
Adapting the HOPE Online Support Intervention to Increase Uptake of Medications for Opioid Use Disorder

In a randomized controlled trial, with 3, 6-month and 1-year follow-up, this application aims to explore whether and how the HOPE intervention can be adapted to increase MOUD uptake among OUD patients, assess the effectiveness of using HOPE to increase MOUD requests, and analyze online community data to improve future …

  • 0 views
  • 03 Apr, 2021
  • 1 location
None
A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder

opioid treatment and in sustaining opioid abstinence compared to the daily sublingual (under the tongue) buprenorphine formulation at a target dose of 16-24 mg (standard of care). This is an open-label

  • 31 views
  • 21 Jun, 2021
  • 23 locations