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Found 510 clinical trials
Featured trial
Study Seeking Patients with Opioid Use Disorder

Study Seeking Patients with Opioid Use Disorder

  • 25 Mar, 2021
  • 1 location
Featured trial
A Washington University research study is currently enrolling pregnant or newly post-partum participants.

The purpose of the study is to gain a better understanding of the impact of early life exposure to different substances on infant brain and behavioral development.  

  • 23 Nov, 2020
  • 1 location
Patient Decision Aid for Opioid Use Disorder

The aim of the study is to test the effectiveness of the Patient Decision Aid for Opioid Use Disorder (PtDA-MAT) by conducting a stepped-wedge cluster-randomized trial in CA H&SS (stratified

narcotic use
drug use
substance use
  • 24 Nov, 2021
  • 1 location
Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0)

Through CTN-0076-Ot (Clinical Decision Support for Opioid Use Disorders in Medical Settings: Pilot Usability Testing in an EMR (COMPUTE)), our team has iteratively developed and piloted a web

  • 08 Apr, 2022
  • 3 locations
A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder (VA-BRAVE)

, randomized, controlled trial including 900 Veterans with opioid use disorder (OUD) recruited over 3 years and followed actively for 52 weeks. There are a number of secondary objectives that will be studied

  • 17 Jun, 2022
  • 18 locations
Adapting the HOPE Online Support Intervention to Increase Uptake of Medications for Opioid Use Disorder (HOPE MOUD)

In a randomized controlled trial, with 3, 6-month and 1-year follow-up, this application aims to explore whether and how the HOPE intervention can be adapted to increase MOUD uptake among OUD patients, assess the effectiveness of using HOPE to increase MOUD requests, and analyze online community data to improve future …

  • 29 May, 2022
  • 1 location
Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

This is a two phase study investigating combinations of pharmacological and behavioral interventions to optimize the treatment of Opioid Use Disorder (OUD). The Retention Phase will assess

  • 30 Jun, 2022
  • 19 locations
Project MIMIC (Maximizing Implementation of Motivational Incentives in Clinics) (MIMIC)

There is an urgent need for effective treatments for patients with opioid use disorder (OUD). This study will train opioid treatment centers in an evidence-based behavioral treatment called

  • 05 Feb, 2022
  • 11 locations
Opioid Treatment and Peer Recovery Support (JCOIN)

Determine whether a facilitated local change team intervention improves a probation organization's client-level medication for opioid use disorder (MOUD) outcomes and implementation outcomes

  • 14 Mar, 2022
  • 3 locations
Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

This is a multi-centre, open-label RCT at four Emergency Departments (EDs) in British Columbia and Alberta. The purpose of the current study is to compare the effectiveness of buprenorphine/naloxone microdosing and standard dosing take-home induction regimens at enabling patients to successfully complete the induction regimen, and at retaining patients on …

  • 10 Aug, 2021
  • 4 locations