Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
I am looking for
added new label for I am looking for
Advanced Filters
Found 57 clinical trials
The Effectiveness of Pleuran in Treatment of Acute Gastroenteritis in Children (EPTAGE)

Acute gastroenteritis (AGE) is one of the most common causes of children's morbidity and mortality globally. Oral or intravenous rehydration is the only effective treatment in reducing morbidity and mortality rates in AGE. However, new attempts to identify other therapeutic methods to reduce the symptoms of diarrhea are of interest. …

  • 15 Mar, 2022
  • 1 location
Impact of a Minimally Invasive Approach to Laparoscopic Hysterectomy on Postoperative Recovery

Background Managing perioperative stress, including endocrino-metabolic changes and, inflammatory and pain responses, is a major challenge to improve patient's recovery. Currently, minimally invasive surgical procedures combined with multimodal analgesia are commonly used to increase the quality of postoperative period. Purpose To demonstrate that a minimally invasive approach including low insufflation …

  • 09 Nov, 2021
  • 1 location
Evaluation of Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia (ELSA Trial)

The use of intravenous lidocaine in continuous infusion in the perioperative period is associated with a reduction in postoperative pain scores, opioid use, incidence of nausea and vomiting, among other favorable outcomes. However, this therapeutic intervention has not yet been adequately evaluated by clinical trials when associated with regional anesthesia. …

regional anesthesia
postoperative pain
  • 06 Aug, 2021
  • 1 location
Erector Spinae Plane Block Versus Serratus Anterior Block on Post Mastectomy Pain Syndrome

Breast cancer is the most common malignancy among females. Nearly 40-60% of breast surgery patients experience severe acute postoperative pain, with severe pain persisting for 6-12 months in almost 20-50% of patients (post mastectomy pain syndrome) which is defined according to International Association for the Study of Pain (IASP) as …

pain syndromes
breast surgery
postoperative pain
  • 22 Mar, 2022
  • 1 location
Inter-fascial Plane Between the SArtorius Muscle and FEmoral Artery (ISAFE) (ISAFE)

Total knee arthroplasty (TKA) is a frequent performed surgery. Adequate pain management is an important feature. Analgesic duration of single shot nerve blocks is limited to no more than 24h. Conversely, the use of continuous nerve block (CNB) through a perineural catheter and infusion of local anesthetic may increase duration …

Accepts healthy volunteers
  • 06 May, 2022
  • 1 location
Uterine Serous Carcinoma and Adjuvant Combined Intraperitoneal Chemotherapy and Radiation

Uterine serous carcinoma (USC) is an uncommon, but aggressive variant of endometrial carcinoma that has poor response to standard therapy. After staging and surgery, radiation therapy and/or chemotherapy is recommended to treat patients at high risk for recurrence. In advanced stage and recurrent setting, high risk uterine cancer mirrors ovarian …

ovarian cancer
  • 25 Nov, 2021
  • 1 location
Impact of Preoperative Fasting on Intraoperative Glycemic Homeostasis and Enhanced Recovery in Children (GLYNEMCaen)

In 2018, the main societies of anesthesia (European Society Anaesthesiology, European Society Pediatric Anesthesia, and Association des Anesthésistes Réanimateurs Pédiatriques d'Expression Française) changed the current recommendations for preoperative fasting time in children, reducing the time to last intake of clear liquids from two to one hour before anesthetic induction. Prolonged …

  • 29 Jul, 2022
  • 1 location