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Found 57 clinical trials
Cooling Helmets to Decrease Concussion Symptoms (ColdCon)

Current therapy of Mild traumatic brain injuries (TBI) revolves around symptomatic care, rest, and return to school/sport/work after symptoms have resolved. The standard intervention for sufferers of mild traumatic brain injury is brain rest, which aims to decrease symptom intensity and duration, prevent re-injury and second impact syndrome via cessation …

  • 0 views
  • 12 Aug, 2022
  • 1 location
Dexmedetomidine Wound Infiltration in Cesarean Section

The effects of four different wound infiltration protocols in cesarean section will be investigated on parturient' pain intensity, PCA morphine consumption given, side effects and parturient' overall satisfaction. One group will receive for wound infiltration dexmedetomidine, the second ropivacaine, the third dexmedetomidine combined with ropivacaine, while the last one will …

ropivacaine
morphine
dexmedetomidine
cesarean section
  • 1 views
  • 22 Jul, 2022
  • 1 location
A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty

Adding a single preoperative dose of gabapentin to the standard pain regimen will reduce postoperative opioid consumption within the first 72 hours in patients undergoing rhinoplasty.

  • 0 views
  • 29 Sep, 2021
  • 1 location
Anesthetic Premedication With a Cannabis Extract (Cannapremed) (Cannapremed)

Clinical evidence about the effects of cannabis in a perioperative setting or for the management of acute pain is rather scarce, mostly consisting of case report-based opinions on adverse events during or after general anesthesia after smoking cannabis, experimental pain trials in healthy volunteers, and a few clinical trials using …

antiemetics
postoperative pain
depression
patient-controlled analgesia
nausea
  • 135 views
  • 11 Apr, 2022
  • 1 location
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations (BBESPB)

Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain. Development and implementation in clinical practice perioperative intensive care protocols for surgical correction of spinal deformities.

epinephrine
intubation
dexamethasone
acute pain
anesthesia
  • 0 views
  • 20 Sep, 2022
  • 1 location
A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients

This is a phase 1, open-label, single centre study of investigational drug selinexor in participants with soft tissue sarcomas that cannot be treated with standard therapies. Selinexor has been given to 3111 participants with cancer to date including 142 sarcoma patients. Early findings have shown that selinexor is effective in …

soft tissue sarcoma
kidney function tests
neutrophil count
cancer
leiomyosarcoma
  • 0 views
  • 18 Apr, 2022
  • 1 location
Radiosensitizing Effect of Nelfinavir in Locally Advanced Carcinoma of Cervix (NELCER)

The primary aim of the trial is to study the impact of nelfinavir on 3 year disease free survival in patients with advanced carcinoma of cervix receiving standard chemoradiation (Cisplatin and Radiotherapy). There will be two study groups. One group will receive standard treatment (concurrent chemoradiation and brachytherapy) & other …

  • 1 views
  • 12 Mar, 2022
  • 1 location
Effects of TIVA Versus Inhalational Anaesthesia on Circulating Tumour Cells in Hepatocellular Carcinoma Patients

More than 80% of patients with cancer will be exposed to anaesthesia at some point in their treatment. There is increasing evidence that perioperative events, including the type of anaesthesia drugs utilised, have an impact on cancer recurrence and metastases. Although potentially and theoretically curative, surgical resection, manipulation and trauma …

hepatectomy
cancer
metastasis
carcinoma
  • 0 views
  • 08 Oct, 2021
  • 1 location
Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery.

The aim of the study is to investigate the analgesic effects of the subcutaneous wound infiltration with tramadol, ketamine, dexamethasone, dexmedetomidine and midazolam as adjuvant to ropivacaine, compared to ropivacaine alone in patients undergoing Video-Assisted thoracoscopic Surgery (VATS) procedures.

ropivacaine
analgesia
dexmedetomidine
ketamine
analgesics
  • 3 views
  • 21 Jul, 2022
  • 1 location
Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis Surgery

This is a single-center study comparing the effect of intravenous (IV) Lignocaine given throughout posterior spinal fusion surgery on the reduction of morphine usage during postoperative period in adolescent idiopathic scoliosis (AIS) patients.

  • 0 views
  • 26 Jun, 2021
  • 1 location