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Found 57 clinical trials
Celecoxib in Postoperative Analgesia for Radius Fracture Surgery

Patients scheduled for elective osteosynthesis of the distal radius will be randomized to receive celecoxib 100 mg orally (PO) at 6 in the morning before surgery and every 12 hours for 2 days thereafter, or a placebo pill in the same regimen. After surgery under general anaesthesia, they will receive …

  • 0 views
  • 09 Apr, 2022
  • 1 location
Comparing TAP Blocks Bupivacaine, and Placebo for Plane (CLEVELAND)

The study will prospectively compare the analgesic efficacy of TAP blocks with liposomal bupivacaine, plain bupivacaine, and placebo in patients who are scheduled for major abdominal surgery. The primary aim is to assess the duration of the local analgesia (determined by pinprick and cold) in all four quadrants. Comparing opioid …

  • 0 views
  • 15 Mar, 2022
  • 1 location
Quadratus Lumborum Block Versus Transversus Abdominis Block

The advent of laparotomy replacement by minimally invasive techniques brought the obvious benefit of postoperative pain reduction. The application of transversus abdominis block has already demonstrated to reduce postoperative pain in laparoscopic hysterectomy. The comparison between it and quadratus lumborum block in cesarean sections showed that the latter was superior …

postoperative pain
remifentanil
pain relieving
propofol
levobupivacaine
  • 0 views
  • 08 Nov, 2021
  • 1 location
Caudal vs Local Anesthesia in Hypospadias (CLASH)

Hypospadias is one of the most common congenital malformations of the genitalia in boys, and is typically managed by surgical intervention. During pediatric urological surgery, caudal anesthesia is one of the most common regional anesthetic techniques used. Also known as caudal block, it has been shown to be a safe …

  • 0 views
  • 24 Apr, 2022
  • 1 location
Chemoembolization (Lifepearls-Irinotecan) in Patients With Colorectal Cancer and Metastatic Disease (LIVERPEARL)

Non-commercial, prospective, randomized, multicenter, national, phase II, open-label comparative clinical trial. The patients will be randomized in a 1: 1 ratio in two arms: Control arm. Systemic chemotherapy with FOLFOX6m + monoclonal Ab Experimental arm. Systemic chemotherapy with FOLFOX6m + monoclonal Ab + Intra-arterial liver chemotherapy with LIFEPEARLS-IRINOTECAN (catheterization and …

  • 0 views
  • 23 Mar, 2022
  • 7 locations
Intrathecal Morphine for Cesarean Delivery

This is a randomized double blinded non-inferiority study comparing the duration of pain relief when patients receive one of three doses of spinal morphine. Enrolled patients will be randomly assigned to receive either 50 mcg, 150 mcg, or 250 mcg. All patients will receive standardized postoperative care, including multimodal analgesia. …

pain relief
morphine
opioid
analgesia
pain relieving
  • 0 views
  • 21 Mar, 2022
  • 1 location
The Optimization of Antiemetic Regimen for C-RINV in LA-HNSCCs

This study sought to investigate the efficacy and safety of a three-drug combination antiemetic regimen of olanzapine combined with aprepitant and palonosetron for the prevention of chemoradiotherapy-induced nausea and vomiting in locally advanced head and neck squamous cell carcinoma.

aprepitant
carcinoma
olanzapine
cavity
nausea
  • 0 views
  • 21 Mar, 2022
Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients (TRASTS)

Phase I-II trial that combines trabectedin plus radiotherapy for tumor reduction response measure in two cohorts of patients: Cohort A: Patients with diagnosis of non-operable or unresectable or not oncologically recommended metastasectomy of limited to lung metastases soft tissue sarcoma. Cohort B: Patients with locally advanced resectable Myxoid Liposarcoma. Cohort …

synovial sarcoma
measurable disease
leiomyosarcoma
myxofibrosarcoma
undifferentiated pleomorphic sarcoma
  • 25 views
  • 17 Jun, 2022
  • 13 locations
Cooling Helmets to Decrease Concussion Symptoms (ColdCon)

Current therapy of Mild traumatic brain injuries (TBI) revolves around symptomatic care, rest, and return to school/sport/work after symptoms have resolved. The standard intervention for sufferers of mild traumatic brain injury is brain rest, which aims to decrease symptom intensity and duration, prevent re-injury and second impact syndrome via cessation …

  • 0 views
  • 04 Oct, 2022
  • 1 location
IPACK or Selective Tibial Nerve Block for ACL Reconstruction With an Adductor Canal Block (TIPACK)

The purpose of this study is to compare the analgesic efficacy of the combination of an adductor canal and selective tibial nerve blocks versus adductor canal block and IPACK after ACL reconstruction under general anaesthesia.

  • 0 views
  • 04 Oct, 2022
  • 1 location