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Found 57 clinical trials
The Ondansetron Premedication Trial in Juvenile Idiopathic Arthritis (OPT-JIA)

drug Ondansetron, reduces nausea and vomiting and increases the proportion of children able to continue methotrexate. By preventing nausea before it starts, the investigators hope to give kids and

uveitis
methotrexate
swelling
arthritis
  • 42 views
  • 18 Feb, 2022
  • 2 locations
Trial of Ondansetron as a Parkinson's HAllucinations Treatment (TOP HAT)

TOPHAT (Trial of Ondansetron as a Parkinson's HAllucinations Treatment) is a double blind, individually randomized, placebo-controlled, parallel group, flexible dose trial of ondansetron (8-24mg

a 12
parkinson's disease
hallucinations
memantine
antipsychotic agents
  • 0 views
  • 17 May, 2022
  • 19 locations
Examining the Effect of Ondansetron on Bowel Prep Success

This is a pilot randomized-controlled trial assessing the utility of ondansetron for improving pediatric pre-colonoscopy bowel prep outcomes using the boston bowel preparation score, as well as

ondansetron
  • 0 views
  • 10 Jul, 2022
  • 1 location
Effect of Ondansetron on Spinal-induced Hypotension for Percutaneous Nephrolithotomy

reflex and is mediated by serotonin receptors (5_HT3) located on the vagus nerve and within the wall of the cardiac ventricles. Ondansetron; an antiemetic drug used for treatment of perioperative

  • 0 views
  • 28 Jul, 2022
  • 1 location
BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron

Patients undergoing either an autologous or allogeneic hematopoietic stem cell transplant (HSCT) and receiving preparative chemotherapy experience a considerable amount of chemotherapy-induced nausea and vomiting (CINV). Current strategies at reducing CINV in this patient population are suboptimal due to lack of efficacy and supportive evidence, potential for increased adverse events, …

ondansetron
antiemetics
quetiapine
dexamethasone
butyrophenone
  • 1 views
  • 16 Jun, 2022
  • 1 location
Validating the Effect og Ondansetron and Mirtazapine in Treating Hyperemesis Gravidarum (VOMIT)

The aim is to investigate the efficacy of mirtazapine and ondansetron as treatment for hyperemesis gravidarum(HG). The setup is a double-blind multicenter trial where patients suffering

Accepts healthy volunteers
  • 82 views
  • 14 Jun, 2022
  • 5 locations
Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia

sensitivity to nutrients in the small intestine. As part of this investigation, a medication called ondansetron will also be studied to determine its effects on gastrointestinal function and associated

diabetes
gastrointestinal symptoms
discomfort
ondansetron 8 mg
nausea
  • 5 views
  • 02 Jun, 2022
  • 1 location
Value of Ondansetron Medication vs Inhaled Isopropyl Therapy in the Emergency Department (VOMIITED) (VOMIITED)

This study will compare two different ways to relieve nausea and vomiting in the Emergency Department. The usual treatment for nausea/vomiting is a drug called Zofran, but new studies have suggested that smelling alcohol pads can also help to relieve nausea and vomiting.

vomiting
zofran
nausea
ondansetron
  • 47 views
  • 29 Apr, 2022
  • 2 locations
Study of Pyridostigmine With Ondansetron in Subjects With Anti-AchR Positive Myasthenia Gravis

This is a phase II, single center, randomized, double-blind, placebo-controlled, study in patients with a diagnosis of anti-AchR antibody positive myasthenia gravis.

ondansetron
immune globulin
pyridostigmine
  • 14 views
  • 15 May, 2022
  • 1 location
The Efficacy of Adjunctive Use of Ondansetron in Patients With Sepsis and Septic Shock

-hydroxytryptamine in the pathogenesis of sepsis. The aim of the current study is to evaluate the efficacy of ondansetron adjuvant use in patients with sepsis and septic shock.

shock
immunostimulants
severe sepsis
septic shock
inflammatory response
  • 0 views
  • 15 Jun, 2022
  • 1 location