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Found 23 clinical trials
Measuring Omalizumab Responses Using Real-world Evidence (MORRE) Study

. Coordinators will record any medication changes or reported medication side effects. Determine response to omalizumab therapy. After participants are placed on omalizumab therapy as part of standard

  • 24 Feb, 2021
  • 1 location
Airway Remodeling During Mepolizumab Treatment

Chronic airway changes, such as smooth muscle hypertrophy/hyperplasia, reticular basement membrane (RBM) thickening, goblet cells hyperplasia characterize severe asthma. Chronic inflammation, and especially eosinophilia and T2 cytokines are involved in these structural changes. The aim of this prospective observational study is to assess airway changes, assessed by bronchial biopsies before …

airway remodelling
  • 25 Jan, 2021
  • 1 location
Subjective Sleep Quality and Sleep Disorders in Patients With Severe Asthma

Bronchial asthma is characterized by the presence of symptoms that vary over time and of severity. Asthma symptoms tend to worsen at night and in the early hours of the morning, and the presence of nocturnal symptoms is an important indicator of therapeutic intervention in order to control the severity …

severe persistent asthma
persistent asthma
  • 25 Jan, 2021
  • 1 location