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Found 23 clinical trials
Comparing Treatment Efficacy With Mepolizumab and Omalizumab in Severe Asthma - "Choosebetweenamab".

Mepolizumab is an anti-interleukin-5 ( IL-5) monoclonal antibody that neutralizes IL-5 and reduces eosinophil counts in both sputum and blood. Omalizumab is an anti-immunoglobulin E (IgE

  • 0 views
  • 26 Jan, 2021
  • 1 location
Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic Participants

(DBPCFC), after treatment with either omalizumab or placebo for omalizumab.

omalizumab
epinephrine
immunoglobulin
skin prick test
skin pricking
  • 100 views
  • 27 Jan, 2021
  • 9 locations
Treatment With the Anti-IgE Monoclonal Antibody Omalizumab in Women With Asthma Undergoing Fertility Treatment. - A Proof of Concept Study.

). Treatment with omalizumab stabilizes the eosinophilic disease, through the systemic and most likely the anti-inflammatory pathways, which indicate a promising possibility to increase pregnancy rate. In a

omalizumab
eosinophil count
diabetes
atopy
intracytoplasmic sperm injection
  • 20 views
  • 25 Jan, 2021
  • 1 location
Preventing Asthma in High Risk Kids

omalizumab (anti-IgE) for two years will prevent the progression to childhood asthma, as reflected by a reduction in the prevalence of active asthma in the Final 12 months during 2 year observation period

wheezing
childhood asthma
anti-ige
omalizumab
  • 218 views
  • 28 Jan, 2021
  • 13 locations
Protection From Food Induced Anaphylaxis by Reducing the Serum Level of Specific IgE (Protana).

reaction to occur is therefore hypothesized to increase by reducing the level of specific IgE to the relevant food allergen. Therapy with Omalizumab has proven efficacious in lowering the level of

atopic dermatitis
anaphylaxis
omalizumab
epinephrine
atopy
  • 9 views
  • 25 Jan, 2021
  • 1 location
Clinical Study Using Biologics to Improve Multi OIT Outcomes

Food allergy (FA) is a serious public health concern that causes potentially-life threatening reactions in affected patients. The prevalence of food allergy in the United States (U.S.) has increased substantially and now affects 15 million patients:4-8% of children (6 million children, 30% with multiple food allergies) and about 9% of …

allergy test
prick skin
skin prick
biological factors
milk allergy
  • 57 views
  • 26 Jan, 2021
  • 3 locations
Dupilumab in Chronic Spontaneous Urticaria

The purpose of this study is to assess the efficacy in reducing disease activity and safety of Dupilumab in adult patients with chronic spontaneous urticaria (CSU) who are symptomatic despite H1-antihistamine treatment.

urticaria
h1 antihistamine
antihistamines
dupilumab
  • 37 views
  • 23 Jan, 2021
  • 3 locations
Research on Severe Asthma

The French Society for Respiratory diseases (SPLF), through its Asthma and Allergy working group (G2A), wishes to set up a national cohort of severe asthma patients to describe this population and the use of step 4 and 5 treatment. This study also meets the demand for post - registration studies …

  • 5 views
  • 23 Jan, 2021
  • 1 location
Role of Endothelial Cells in the Pathogenesis of Chronic Urticaria.

big impact on the quality of life of patients. Unfortunately, to date CU is not easily controlled by its few existing treatment options (i.e. antihistamines, omalizumab, cyclosporine). This

  • 97 views
  • 24 Feb, 2021
  • 1 location
Wessex Asthma Cohort of Difficult Asthma

Asthma is now widely recognised to be a heterogeneous disease. The last two decades have seen the identification of a number of biological targets and development of various novel therapies. Despite this, asthma still represents a significant health and economic burden worldwide. Why some individuals should continue to suffer remains …

pulmonary function test
  • 12 views
  • 22 Jan, 2021
  • 3 locations