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Found 19 clinical trials
Effect of Omalizumab (Xolair) in Treatment of Patients With AERD and Allergy Asthma

Double blind protocol treatment of 2/3 of the patients with omalizumab and 1/3 placebo administer for 4 months. Patients selected for the study must have both aspirin exacerbated

rhinitis
aspirin
respiratory disorder
allergic asthma
omalizumab
  • 37 views
  • 07 Nov, 2020
  • 1 location
Study of Magnitude and Prediction of Response to Omalizumab and Mepolizumab in Adult Severe Asthma.

Pragmatic trial to define the magnitude and the predictive factors of the response to omalizumab and mepolizumab in adult patients with severe refractory asthma and eligible to both therapies

  • 9 views
  • 26 Jan, 2021
  • 13 locations
A Pragmatic Study to Investigate the Efficacy and Safety of Mepolizumab in Severe Uncontrolled Asthma in Brazil

The anti-interleukin-5 monoclonal antibody mepolizumab is approved as an add-on therapy in Europe, Canada, USA, and other countries, to standard of care for the treatment of patients with severe eosinophilic asthma. Mepolizumab has been shown to reduce exacerbation rates and dependency on oral corticosteroid use in clinical trials in patients …

  • 0 views
  • 23 Jan, 2021
  • 2 locations
Dupilumab for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine and Who Are na ve to Intolerant of or Incomplete Responders to Omalizumab

Primary Objective: To demonstrate the efficacy of dupilumab in study participants with CSU who remain symptomatic despite the use of H1 antihistamine (Study A: omalizumab nave; Study B

urticaria
dupilumab
antihistamines
h1 antihistamine
angioedema
  • 10 views
  • 18 Apr, 2021
  • 82 locations
Omalizumab to Accelerate a Symptom-driven Multi-food OIT

This study will determine the dose-related efficacy of a 20-week treatment of omalizumab started 8 weeks before the onset of a symptom-driven multi-food oral immunotherapy (OIT) protocol at

  • 6 views
  • 29 Jan, 2021
  • 6 locations
Behandling af Boern Med Foedevareallergi Med Omalizumab (Xolair)

Food allergy is a common disease in childhood affecting up to 8% of children in Westernized countries. About 30 percent of children with food allergies are allergic to more than one food, most often milk, egg, wheat, peanut and tree nut. Peanut and hazelnut are common triggers of severe and …

xolair
omalizumab
allergen
anaphylaxis
  • 0 views
  • 25 Jan, 2021
  • 1 location
Preclinical Studies of Omalizumab in Chronic Rhinosinusitis With Nasal Polyposis

The goal of this study is to examine the mechanism of action of omalizumab in ex vivo tissue culture of whole human nasal polyps from patients with chronic rhino sinusitis with nasal polyposis

  • 0 views
  • 27 Jan, 2021
  • 2 locations
Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic Participants

(DBPCFC), after treatment with either omalizumab or placebo for omalizumab.

skin prick test
epinephrine
skin pricking
omalizumab
allergen
  • 100 views
  • 20 Jun, 2021
  • 9 locations
Comparing Treatment Efficacy With Mepolizumab and Omalizumab in Severe Asthma - "Choosebetweenamab".

Mepolizumab is an anti-interleukin-5 ( IL-5) monoclonal antibody that neutralizes IL-5 and reduces eosinophil counts in both sputum and blood. Omalizumab is an anti-immunoglobulin E (IgE

  • 0 views
  • 26 Jan, 2021
  • 1 location
Preventing Asthma in High Risk Kids

omalizumab (anti-IgE) for two years will prevent the progression to childhood asthma, as reflected by a reduction in the prevalence of active asthma in the Final 12 months during 2 year observation period

wheezing
omalizumab
childhood asthma
anti-ige
  • 218 views
  • 10 May, 2021
  • 14 locations