Found 179 clinical trials
A 26-Week, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Effects of Daily Administration of AC-1204 in Participants With Mild to Moderate Alzheimer's Disease (AD) With an Optional 26-Week Open Label Extension
A 26-Week, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Effects of Daily Administration of AC-1204 in Participants With Mild to Moderate Alzheimer's Disease (AD) With an Optional 26-Week Open Label Extension
- 171 views
- 08 Dec, 2020
- 1 location
NIDA-CTN-0100: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)
This is a two phase study investigating combinations of pharmacological and behavioral interventions to optimize the treatment of Opioid Use Disorder (OUD). The Retention Phase will assess strategies for improving retention on buprenorphine (BUP) and extended-release injectable naltrexone (XR-NTX). The Discontinuation Phase will assess which approaches are most likely to …
- 76 views
- 14 Oct, 2022
- 18 locations
Effects of MDMA-like Substances in Healthy Subjects
subjective effects they may also produce negative subjective drug effects including anxiety in particular at the onset of the subjective response and the rapid onset of euphoria may increase the risk of
- 50 views
- 05 Jan, 2022
- 1 location
Multi-center, Open-label, Phase 1b Clinical Trial to Evaluate the Safety, Tolerability, and Exploratory Efficacy of TEW-7197 in Combination With FOLFOX in Patients With Metastatic Pancreatic Ductal Adenocarcinoma Who Have Failed First-Line Gemcitabine and Nab-Paclitaxel (MP-PDAC-01)
>Subjects who have a history of or are suspected of drug abuse Female subjects of child-bearing potential who have a positive result on a pregnancy test at screening or are unable to agree to use
- 1 views
- 29 Jun, 2022
- 1 location
Linking Services to Patient Needs for Improved Patient Outcomes (CASPAR)
The purpose of this study is to determine if providing a county specific electronic resource guide with low and no cost services to outpatient substance abuse counselors, results in more and better matched services for the clients. These services are not limited to substance abuse treatment, they include such services …
- 149 views
- 07 Nov, 2020
- 1 location
Regional Partnership for Pregnant Women at Risk of Substance Misuse and Their Newborns
This study recruits pregnant women and new mothers who are at risk of substance use concerns during pregnancy or delivery. These women are followed for 6 months and randomized into two groups; they may receive services as usual, or enhanced services. Enhanced services include evidence based interventions and case management …
- 1 views
- 03 Apr, 2023
- 1 location
Developing Robust Treatment Options for Mal de Débarquement Syndrome
Mal de Débarquement Syndrome (MdDS) is an under-recognized balance disorder, which is manifested by persistent false sensations of oscillatory self-motion (rocking/swaying) and/or pulling in a specific direction (gravitational pull). Patients with MdDS typically experience additional presumably secondary symptoms, such as heightened sensitivity to visual motion (visually induced dizziness, VID), physical …
- 0 views
- 10 Oct, 2022
- 1 location
Using Telehealth to Improve Outcomes in Veterans at Risk for Suicide
Overview. The investigators will randomize 120 Veterans in this 3-site trial over 16 months. Eligible Veterans will include those to be discharged for a hospitalization for suicidal ideation. Baseline data collection and randomization will occur at discharge. The 3 month intervention will have study assessments at 2, 4, 8, and …
- 0 views
- 18 May, 2022
- 2 locations
Mavoglurant in Alcohol Drinking
The purpose of this alcohol-interaction pilot study is to provide information on the effect of mavoglurant on the pharmacokinetics of alcohol and on alcohol responses, including stimulation, sedation, intoxication, body sway and physiological responses. The investigators propose to test the effects of 200 mg mavoglurant versus placebo on alcohol related …
- 0 views
- 07 Apr, 2023
- 1 location
Effects of E-cigarette Flavors on Youth TCORS 2.0
This study is an examination of the influence of sweet and cooling flavors on the appeal and abuse potential of nicotine-containing e-cigarettes among susceptible youth.
- 0 views
- 06 Apr, 2023
- 1 location