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Found 299 clinical trials
Addressing Insufficient PAP Use in Older Veterans

Sleep apnea is a common problem in middle-aged and older Veterans that is associated with poor nighttime sleep, more daytime sleepiness, poor functioning and worse quality of life. The recommended therapy for most patients with sleep apnea is positive airway pressure (PAP) therapy; however, over time many patients prescribed PAP …

apnea-hypopnea index
obstructive sleep apnea
  • 25 Mar, 2022
  • 1 location
OFA in Thoracic Surgery

to investigate the efficacy and safety of opioid-free anesthesia for non-small-cell lung cancer resection and its underlying clinical value

  • 15 May, 2022
  • 2 locations
Effect of Video-Based Coaching on Resident Laparoscopic Surgical Skills

Randomized controlled trial to evaluate the effect of video-based coaching on Obstetrics and Gynecology residents' efficiency, proficiency, and confidence in performing laparoscopic salpingectomy.

Accepts healthy volunteers
  • 09 Nov, 2021
  • 1 location
Rebreathing-induced Hypoxia and Glucose Levels

The aim of this research project is to determine the effect of repeated maximal voluntary apneas on glucose uptake during an oral glucose tolerance test in healthy individuals, individuals with prediabetes and patients with type 2 diabetes.

Accepts healthy volunteers
  • 30 Jun, 2022
Predictors of Response to Insomnia Treatments for Gulf War Veterans

The purpose of this study is to evaluate the efficacy and effectiveness of Sleep Restriction (SR) and Cognitive Therapy (CT) in Gulf War Veterans with insomnia. The primary hypothesis is that the efficacy of these treatments will depend upon an individual subject's baseline characteristics. For SR we expect that baseline …

sleeping pill
sleep restriction therapy
post-traumatic stress disorder
behavior therapy
  • 25 Mar, 2022
  • 3 locations
Effect of Coffee and Tea Consumption on Adolescent Weight Control

Introduction: The influence of tea or coffee supplementation on body weight in adolescents has never been tested. The aim of the present study was to investigate the effect of tea and coffee consumption on body weight and body fat in an obese adolescent population. Methods: Randomized clinical trial, parallel group …

  • 25 Mar, 2022
Remdesivir, Long-covid and Quality of Life

SOLIDARITY Finland Long-COVID trial assesses the effects of remdesivir + standard of care (SoC) vs. only SoC on long-COVID symptoms and quality of life (QoL) using questionnaires at one and two years post-discharge. Objectives i) Long-COVID symptoms To investigate the effect of remdesivir (vs. SoC) on the occurrence of symptoms …

  • 11 May, 2022
  • 1 location
A Post-market Clinical Follow up of the Genio™ System for the Treatment of Obstructive Sleep Apnea in Adults (EliSA)

The primary objective of this study is to confirm the safety and clinical effectiveness of the Genio™ system, used according to its instructions for use, in moderate to severe Obstructive Sleep

body mass index
  • 21 Mar, 2022
  • 6 locations
DISE: Phenotyping Obstruction Patterns

Drug-induced sleep endoscopy (DISE) represents an opportunity to evaluate the upper airway in sleep-like conditions. In its current clinical form, however, DISE does not routinely determine the functional impact of anatomic and neuromuscular factors on airflow obstruction. The investigators will apply nasal pressure (CPAP) during DISE to generate pressure-flow and …

  • 02 Dec, 2021
  • 1 location
Sleep for Stroke Management and Recovery Trial (Sleep SMART)

The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1

ischemic stroke
recurrent strokes
acute coronary syndrome
  • 14 Apr, 2022
  • 106 locations