Found 980 clinical trials
Study to Assess the Efficacy Safety and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-2)
Primary Objective: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on pulmonary function in former …
- 215 views
- 24 May, 2022
- 51 locations
Albuterol in Patients With Lymphangioleiomyomatosis
Background: Lymphangioleiomyomatosis (LAM) is a rare type of lung disease that occurs almost exclusively in women. In LAM, muscle tissue grows in the lungs and starts to block the flow of air. It is a progressive disease, and in severe cases may require a lung transplant. One possible treatment to …
- 94 views
- 22 Dec, 2020
- 1 location
SEVERE COPD?
North Carolina Clinical Research is enrolling adults 40+ living with severe to very severe COPD fora clinical research study comparing two approved medications.
- 0 views
- 10 Jan, 2022
- 1 location
COPD Exacerbation Research Study
Looking for patients at least 40 years of age who have been diagnosed with COPD and recently had several events of worsening of symptoms.
- 125 views
- 23 Nov, 2020
- 1 location
COPD Research Study for those with currently using inhaled medications (triple therapy) and have required an oral steroid for a flare in breathing 1-2 times in the last 12 months.
This investigational study is enrolling moderate to severe COPD subjects. To qualify you must be on inhaled maintenance medications and have required oral steroids 1-2 times or a hospitalization in the last year. Pulmonary function test will be performed and compensation will be provided for those who qualify.
- 144 views
- 23 Nov, 2020
- 1 location
NO 0050-0637
ICON Early Phase Services is conducting a non-interventional device research study adults age 40+ who are either healthy, or, have chronic obstructive pulmonary disease (COPD). This study is being done to test the potential of using devices to help manage disease symptoms. Participants will complete a screening visit to determine …
- 613 views
- 23 Nov, 2020
- 1 location
A Phase III Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ensifentrine over 24 Weeks in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease.
This study will enroll approximately 800 patients with moderate to severe COPD in 2 subsets. The 24-week subset will enroll approximately 400 patients randomized 1:1 ensifentrine (3 mg): placebo and the 48-week subset will enroll approximately 400 patients randomized 3:1 in order to minimize the number of patients assigned to …
- 164 views
- 23 Nov, 2020
- 1 location
Now Enrolling - Chronic Obstructive Pulmonary Disease (COPD) Research Study
Now Enrolling - Chronic Obstructive Pulmonary Disease (COPD) Research Study
- 573 views
- 20 Jul, 2021
- 3 locations
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate CBP-201 in Adult Patients with Chronic Rhinosinusitis with Nasal Polyps
To evaluate the efficacy of CBP-201 in patients with chronic rhinosinusitis with nasal polyps
- 0 views
- 07 Mar, 2022
- 1 location
Phase III, Double Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Etrolizumab During Induction and Maintenance in Patients With Moderate to Severe Active Ulcerative Colitis Who Are Refractory to or Intolerant of TNF Inhibitors
Phase III, Double Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Etrolizumab During Induction and Maintenance in Patients With Moderate to Severe Active Ulcerative Colitis Who Are Refractory to or Intolerant of TNF Inhibitors
- 184 views
- 25 Mar, 2021
- 1 location