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Found 79 clinical trials
Efficacy and Safety of Carvedilol in Cirrhosis Patients With Uncomplicated Ascites Without High Risk Esophageal Varices

The cumulative risk of refractory ascites is in the order of 20% within five years of the development of ascites. An elevated sinusoidal pressure is essential for the development of ascites, as fluid accumulation does not develop at portal pressure gradient below 8 mm Hg, and rising corrected sinusoidal pressure …

carvedilol
paracentesis
esophageal varices
cytokines
vasopressin
  • 0 views
  • 06 Nov, 2021
  • 1 location
NR in Chemo-induced Peripheral Neuropathy

The purpose of this single-arm phase II trial is to determine whether nicotinamide riboside (NIAGEN) prevents the progression of peripheral sensory neuropathy in patients receiving infusions of paclitaxel or nab-paclitaxel for the treatment of metastatic breast cancer or recurrent platinum-resistant ovarian, endometrial, peritoneal, or fallopian tube cancer.

estradiol
bevacizumab
paclitaxel
breast cancer
herceptin
  • 77 views
  • 09 Feb, 2022
  • 2 locations
Topical Menthol Application in Chemotherapy-Related Peripheral Neuropathy in Patients With Breast Cancer

Peripheral neuropathy resulting from chemotherapy is a problem that concerns not only the individual but also their relatives and all healthcare personnel responsible for care. Studies to be carried out in this area are important in terms of providing evidence for nurses' practices and supporting the individual by alleviating the …

cancer
paclitaxel
  • 0 views
  • 26 Jul, 2022
  • 1 location
Systemic Absorption of Lidocaine After Hematoma Block

This study will measure in children how much numbing medicine, lidocaine, is absorbed into the bloodstream after it is injected into a blood clot (hematoma) around a forearm fracture for pain control when the broken bone is moved back into place (fracture reduction). This is called a hematoma block and …

clot
Accepts healthy volunteers
  • 0 views
  • 27 Nov, 2021
  • 1 location
Feasibility of Prehab for Lumbar Spinal Stenosis

The literature has shown evidence of the effectiveness of prehabilitation programs on post-operative recovery for musculoskeletal conditions; however, evidence for prehabilitation for lumbar spinal stenosis (LSS) is limited. Investigators have found that there is very low to low quality evidence for the effect of prehabilitation interventions for improving outcomes following …

  • 0 views
  • 22 Apr, 2022
  • 3 locations
tDCS and Pain Associated With Diabetic Neuropathy

The purpose of this study is to investigate the effects of anodal transcranial direct current stimulation (tDCS) on pain intensity associated with diabetic neuropathy. The investigators will conduct real tDCS or sham, over the left dorsolateral prefrontal cortex (DLPFC) during 6 separated days. They will evaluate pain intensity, sleep quality, …

anxiety
hemoglobin a1c
diabetic peripheral neuropathy
chronic pain
peripheral neuropathy
  • 26 views
  • 01 Mar, 2022
  • 1 location
Device-Less Technique in Islet Transplantation

Islet transplantation is an effective modality for treating type 1 diabetes. Despite marked progress in clinical islet transplantation with the achievement and maintenance of insulin independence in over half of recipients up to 5 years, transplant approaches are limited to those that struggle to control their diabetes. Furthermore, this approach …

hypoglycemia
diabetic ketoacidosis
diabetes
plasma glucose
insulin
  • 0 views
  • 27 May, 2022
  • 1 location
Effects of Transcutaneous Nerve Electrostimulation (TENS) of Acupuncture Points on Pulmonary Function and Dyspnea Symptoms in Patients With Pulmonary Nodules (LUNG TENS)

The ancient use of acupuncture as a treatment modality of traditional Chinese medicine has also been proven effective in Western medicine. The use of this treatment tool for pain control is already proven in the literature and today is considered an important adjuvant for this purpose. However, the ancient texts …

walk test
pulmonary disease
analgesia
traditional chinese medicine
pulmonary function test
  • 4 views
  • 14 Feb, 2022
Effects of Nitrate-rich Beetroot Juice in Pregnant Women With High Blood Pressure (NITBEETPE)

BACKGROUND: Preeclampsia (PE) is a serious syndrome that affects 3-7% of all pregnant women. PE is characterized by hypertension and kidney problems after the 20th week of pregnancy and is associated with an increased risk of serious cardiovascular complications including death in both mother and fetus. The underlying disease mechanisms …

renal function
nitric oxide
hypertension
cardiovascular complications
Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over study testing two different classes of anti arrhythmic drugs (AADs). This pilot and feasibility study will provide preliminary data for a larger study in which the investigators will …

antiarrhythmic drug
flecainide
fibrillation
sotalol
  • 319 views
  • 08 Jul, 2022
  • 1 location