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Found 77 clinical trials
abSorbable vErsus Non-absorbable SuturEs for Wound Closure in Carpal Tunnel Release (SENSE)

Carpal Tunnel Syndrome is a prevalent condition, up to 9% in women and 0.6% in men. Surgical decompression in the most effective treatment. After surgery, approximately 1,8% of the patients develop a wound infection. Possibly, the type of sutures used can influence the prevalence of wound infection. In this RCT …

Accepts healthy volunteers
  • 0 views
  • 05 Jul, 2022
  • 2 locations
Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy (ATNEC)

The aim of this study is to assess whether, omitting further axillary treatment (ALND and ART) for patients with early stage breast cancer and axillary nodal metastases on needle biopsy, who after NACT have no residual cancer in the lymph nodes on sentinel node biopsy, is non-inferior to axillary treatment …

estrogen receptor
cancer
axillary lymph node dissection
HER2
estrogen
  • 839 views
  • 14 Jun, 2022
  • 49 locations
Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)  

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis (PPMS) Secondary Objectives: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety …

disease or disorder
oligoclonal bands
  • 108 views
  • 05 Jul, 2022
  • 49 locations
Positioning for Hip Arthroscopic Surgery to Reduce Postoperative Numbness

perineal numbness. Traction pads, used alone or with a perineal post, can reduce pressure on the perineal area, thus reducing numbness. The investigators hypothesize that positioning hip arthroscopy

  • 0 views
  • 18 Dec, 2021
  • 1 location
PEA for the Relief of Chemotherapy-Induced Peripheral Neuropathy

nerve problem that causes pain, numbness, tingling, or muscle weakness in different parts of the body, and is caused by chemotherapy. PEA may be useful against bothersome nerve symptoms.

cancer
  • 0 views
  • 04 Jul, 2022
  • 1 location
Whole Body Vibration for the Improvement of Health and Functioning in Participants With Chemotherapy-Induced Peripheral Neuropathy

a condition caused by exposure to chemotherapy drugs that may involve numbness/tingling and/or pain in the hands and feet, which can have adverse effects on daily life. Whole body vibration may

cancer
numbness
peripheral neuropathy
neuropathy
paresthesia
  • 137 views
  • 16 Mar, 2022
  • 1 location
Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer

This phase II/III trial studies the best dose of duloxetine and how well it works in preventing pain, tingling, and numbness (peripheral neuropathy) caused by treatment with oxaliplatin in

  • 319 views
  • 07 Apr, 2022
  • 559 locations
Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy

surgery for ovarian or endometrial cancer and if it will improve lower extremity function (function of the legs), lessen chemotherapy-induced peripheral neuropathy (CIPN; numbness or tingling in the hands

cancer
carboplatin
paclitaxel
cancer chemotherapy
neuropathy
  • 0 views
  • 14 May, 2022
  • 1 location
The Use of Technology to Improve MS Clinical Trials and Patient Care

Many patients with multiple sclerosis (MS) experience "relapses" of disease activity during which they have increased numbness, weakness, visual problems, or other symptoms. If a person with MS

interferon
teriflunomide
disease or disorder
MRI
weakness
  • 25 views
  • 27 May, 2022
  • 1 location
Granulocyte-Macrophage Stimulating Factor (GM-CSF) in Peripheral Arterial Disease

pain and numbness. The pain is usually worse with exercise and gets better with rest. PAD can raise the risk of getting an infection which could lead to tissue death and amputation. This study is

  • 167 views
  • 28 Oct, 2021
  • 1 location