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Found 14 clinical trials
Tenofovir Alafenamide With Fine Needle Aspiration Biopsy in Chronic Hepatitis B:

The objective of this study is to identify immunological mechanisms that contribute to normalization of liver inflammation in chronic hepatitis B (CHB) patients starting the antiviral nucleoside

  • 0 views
  • 23 Jan, 2021
  • 1 location
HBV Vaccine in Anti-core Positive Donors After LT

Anti-HBc positive liver donors frequently have occult HBV infection, and several studies in HBsAg-negative subjects have shown that there is often the detection in the liver of covalently closed circular DNA (cccDNA). In the setting of liver transplantation and immunosuppresion, grafts from antiHBc positive donors may cause de novo HBV …

  • 0 views
  • 24 Jan, 2021
A RCT of TNF and ENT in the Treatment of Long-term Prognosis With Hepatitis B-related HCC After Curative Resection

This study evaluates the addition of Tenofovir and Entecavir in the treatment of Hepatitis B-related hepatocellular carcinoma after curative resection in adults. Half of participants will receive Tenofovir disoproxil fumarate, while the other half will receive Entecavir.

  • 0 views
  • 24 Jan, 2021
  • 1 location
Chronic Hepatitis b Patients Switch to tAf After Discontinuation of Nucleoside Analogue

We will conduct a phase 4, multicenter, open-label trial at 7 academic centers in Taiwan. Chronic hepatitis B patients receiving oral antiviral therapy (entecavir [ETV], tenofovir disoproxil fumarate [TDF]) for at least 2 years, and fulfil the following nucleos(t)ide analogs discontinuation criteria. After nucleos(t)ide analogs discontinuation, patients had a clinical …

hepatitis
entecavir
fumarate
antiviral therapy
tenofovir
  • 0 views
  • 12 Aug, 2021
  • 7 locations
Extension Study of Carvedilol RCT Study

Patients who have completed 2-years treatment in RCT Study of carvedilol will receive another 2-years extension therapy, aiming to investigate the long-term efficacy of carvedilol for the prevention of esophageal varices in treated HBV cirrhotic patients.

carvedilol
esophageal varices
  • 0 views
  • 01 Sep, 2021
  • 14 locations
TAS-102 in Extrapulmonary Neuroendocrine Carcinoma

The purpose of this study is to test the safety and efficacy of drug, TAS-102 (trifluridine/tipiracil), in patients with extrapulmonary (outside the lung) high-grade neuroendocrine cancer. TAS-102 demonstrated improved survival and tolerability in patients with colorectal cancer and is currently approved by the FDA and marketed under the brand name …

  • 99 views
  • 23 Jan, 2021
  • 1 location
Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Chronic Hepatitis b

This study is to investigate the clinical efficacy and safety of three types of nucleotide/nucleoside analogues in treatment of chronic hepatitis b

entecavir
hepatitis b surface
fumarate
hepatitis b e antigen
tenofovir
  • 0 views
  • 23 Jan, 2021
  • 1 location
Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF

This study is to investigate the clinical efficacy of three types of nucleotide/nucleoside analogues in treatment of HBV-related acute-on-chronic liver failure.

acute on chronic liver failure
prothrombin
hepatitis b antigen
hepatitis
serum total bilirubin level
  • 3 views
  • 23 Jan, 2021
  • 1 location
Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Hepatitis b Virus Related Compensated Cirrhosis

This study is to investigate the clinical efficacy and safety of three types of nucleotide/nucleoside analogues in treatment of hepatitis b virus related compensated cirrhosis.

hepatitis
entecavir
cirrhosis
fumarate
tenofovir
  • 0 views
  • 23 Jan, 2021
  • 1 location
A Prospective Observational Follow-up Study of Nucleoside Treated Patients With Chronic Hepatitis B (OCEAN Study)

This is a prospective, multicentre observational follow-up study of PegIFN treatment unstained response in nucleoside experienced patients with Chronic Hepatitis B.Patients will join this study after finished following clinical trail about A Study of Combination or Sequential Treatment With PEGASYS (Peginterferon Alfa-2a) and Entecavir in Patients With HBeAg Positive Chronic …

interferon
sequential treatment
hepatocellular carcinoma
cirrhosis
combination therapy
  • 16 views
  • 22 Jan, 2021
  • 9 locations