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Found 6 clinical trials
Ribavirin to Enhance Hepatitis B Virus Nucleotide Analog Antiviral Activity

aim of this study is to determine whether combination of Ribavirin and a nucleoside analog is more effective compared to nucleoside analog treatment alone. Enrolled patients will be followed for

nucleoside analog
antiviral therapy
hepatitis d
antiviral drugs
ribavirin
  • 0 views
  • 23 Sep, 2021
  • 2 locations
Study of Chidamide Combined With Cladribine in Refractory/Relapsed Acute Myeloid Leukemia

acute myeloid leukemia. Cladribine is a purine nucleoside analog, which has the ability to inhibit DNA synthesis, repair, induce apoptosis, and has anti-leukemia activity for cells in both

refractory acute myeloid leukemia (aml)
cancer
induction chemotherapy
lymphoma
adult acute myelogenous leukemia
  • 0 views
  • 18 May, 2022
  • 1 location
Study of Fludarabine With Pegylated Liposomal Doxorubicin Versus Pegylated Liposomal Doxorubicin Alone In Patients With Platinum Resistant/Refractory Ovarian Cancer

The purpose of the study is to evaluate the efficacy and toxicity of fludarabine with pegylated liposomal doxorubicin versus pegylated liposomal doxorubicin alone in patients with platinum resistant or refractory ovarian cancer.

doxorubicin
cancer of the ovary
metastasis
measurable disease
solid tumour
  • 4 views
  • 25 Feb, 2022
  • 1 location
Clofarabine Pre-conditioning Followed by Stem Cell Transplant for Non-remission AML

The Investigators would like to study the incidence of complete remission (CR) at day +30 after Clofarabine followed by haploidentical transplant. The conditioning regimen used is Fludarabine, Busulfan (2 doses) or cyclophosphamide (2 doses) and Total Body Irradiation (TBI) with post transplant cyclophosphamide for patients with Acute Myeloid Leukemia (AML) …

transplant conditioning
clofarabine
cyclophosphamide
filgrastim
granulocyte colony stimulating factor
  • 0 views
  • 18 Oct, 2021
  • 1 location
HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer

The purpose of this study is to conduct a Phase I - II clinical trial to extend preclinical studies involving in situ HSV-tk + Valacyclovir gene therapy in combination with brachytherapy for recurrent prostate cancer. This will provide a novel therapeutic approach to prostate cancer and hopefully impact on the …

cancer treatment
recurrent prostate cancer
cancer
external beam radiation therapy
brachytherapy
  • 17 views
  • 21 Jan, 2021
  • 1 location
5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

Background Blood, tissue, and tumor cells contain genes. Genes are made up of DNA. DNA is the instruction book for each cell. In some people with cancer, the genes that might have slowed the growth of their tumor were turned off. Researchers want to see if a new drug can …

advanced cancer
solid neoplasm
solid tumor
primary cancer
metastasis
  • 128 views
  • 11 Aug, 2022
  • 1 location