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Found 53 clinical trials
Xpert MTB/RIF Test in the Diagnosis of Pulmonary Tuberculosis

Currently in Taiwan, most clinicians use sputum smear and culture for the diagnosis of pulmonary tuberculosis (TB) and apply nucleic acid amplification (NAA) test in a selected manner. In 2013

  • 26 Jan, 2021
  • 5 locations
Safety and Efficacy Study of Meningococcal Group B Vaccine rMenB+OMV NZ (Bexsero) to Prevent Gonococcal Infection

This is a Phase II, randomized, observer-blind, placebo-controlled, multi-site trial of the FDA licensed rMenB+OMV NZ vaccine, Bexsero. The targeted study population is men and women 18-50 years of age who are disproportionately vulnerable to N. gonorrhoeae infection. Approximately 2,200 participants are expected to be enrolled to achieve at least …

  • 23 Sep, 2021
  • 7 locations
Trial of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector Ad5-nCoV) in Adults Living With HIV

A randomized, double-blind, placebo -controlled, phase IIb clinical trial to evaluate the efficacy, safety and immunogenicity of one or two doses of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) in adults 18 years of age and older, living with HIV, on stable treatment, and virologically suppressed for at least …

  • 22 Sep, 2021
  • 1 location
The Safety and Pharmacokinetics Study of TAKC-02 Inhalation Solution in Healthy Adult Males.

associated with the onset and exacerbation of several diseases such as inflammatory diseases, metabolic diseases, and malignant tumors. TAKC-02 is a nucleic acid medicine, antisense oligonucleotide, inhibits

  • 02 Sep, 2021
  • 1 location
Improvements Through the Use of a Rapid Multiplex PCR Enteric Pathogen Detection Kit in Children With Hematochezia

will randomly allocate 60 children to either standard care as dictated by the treating physician or to the use of a 22-pathogen, nucleic acid based, 1-hour run time diagnostic test. The study team

  • 26 Jan, 2021
  • 1 location
A Clinical Trial of Silver Diamine Fluoride to Arrest Early Childhood Caries in Young Children

regimen will have plaque samples collected. Samples will be obtained prior to SDF application at baseline, at the first follow-up visit, and at the final visit. Following nucleic acid isolation from

  • 26 Jan, 2021
  • 1 location
Vancomycin for the Treatment of NAAT(+)/Toxin(-) C. Difficile

This study proposes to: Characterize the impact of oral vancomycin on C. difficile loads after end of treatment compared to a placebo group. Determine the effect of oral vancomycin on structural and functional microbiome changes after end of treatment compared to a placebo group. Characterize the impact of oral vancomycin …

vancomycin oral capsule
oral vancomycin
  • 26 Jan, 2021
  • 1 location
Clinical Trial for Registration of HPV Nucleic Acid Genotyping Assay Kit

The objective of this study is to verify the clinical effectiveness of HPV Genotyping Nucleic Acid Assay Kit. This is a multi-center clinical study involving at least three study centers, each

  • 05 Feb, 2021
  • 3 locations
Efficacy and Safety of Antimicrobial Stewardship Intervention in Hospitalized COVID-19 Patients (COVASP)

feedback versus no antimicrobial stewardship intervention on physicians attending to patients with proven SARS-CoV-2 infection confirmed by nucleic acid testing in the preceding 2 weeks of hospitalization

  • 28 May, 2021
  • 4 locations
Sanitation Water and Instruction in Face-washing for Trachoma I/II

. The novel tests include inexpensive, point-of-care nucleic acid amplification tests performed on conjunctival swabs, a lateral flow assay for chlamydia seropositivity tested on dried blood spots, and

  • 11 Jul, 2021
  • 1 location