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Found 93 clinical trials
STereotactic Ablative Radiosurgery of Recurrent Ventricular Tachycardia in Structural Heart Disease

A multicentre trial on clinical effects of radiosurgical ablation of ventricular tachycardia (VT).

  • 0 views
  • 27 Jan, 2021
  • 2 locations
Intracoronary of Nicorandil and Verapamil to Reduce the Occurrence of Periprocedural Myocardial Injury

Percutaneous coronary intervention (PCI) remains the major revascularization strategy for patients with obstructive coronary artery disease (CAD).However,in a substantial number of PCI cases for acute coronary syndrome (ACS) and chronic coronary syndrome (CCS),periprocedural myocardial injury or myocardial infarction (MI) occurs,both these PCI-related complications may be associated with an increased risk …

infarct
atherosclerosis
percutaneous coronary intervention
revascularisation
stenosis
  • 0 views
  • 17 Jun, 2022
  • 1 location
Randomized Double-blind Trial to Study the Benefit of Colchicine in Patients With Acutely Decompensated Heart Failure

Heart failure (HF) is a chronic disease associated with multiple acute decompensations, which are the main cause of hospital admission above 65 years and two thirds of the high costs associated with the disease. Furthermore, in the patient they reflect a phase of clinical instability, with a higher risk of …

  • 0 views
  • 19 Feb, 2021
  • 1 location
Pragmatic Urinary Sodium-based Treatment algoritHm in Acute Heart Failure

Administration of loop diuretics to achieve decongestion is the current cornerstone of therapy for acute heart failure. Unfortunately, there is a lack of evidence of how to guide diuretic treatment. Recently, urinary sodium, as a response measure of diuretic response, has been proposed as a target for therapy. The hypothesis …

  • 0 views
  • 21 Feb, 2021
  • 1 location
The Norwegian Exercise in Atrial Fibrillation Trial (NEXAF)

Atrial fibrillation (AF) patients suffer a high symptom burden and reduced quality of life (QoL), high hospitalization rates and few effective treatment options. They have a high burden of cardiovascular risk factors and events. Lifestyle changes and exercise is a cornerstone of management in most chronic cardiac conditions and holds …

fibrillation
  • 0 views
  • 05 Apr, 2022
  • 3 locations
Stratified Medicine of Eplerenone in Acute MI/Injury (StratMed-MINOCA)

Patients with heart attack or heart injury are tested (angiogram) for blockages in their arteries. Many patients develop heart problems caused by damage to small (microvascular) blood vessels. These issues are also relevant to patients with coronarvirus-19 disease (COVID-19). Eplerenone reduces blood vessel injury and is used to treat heart …

  • 0 views
  • 18 May, 2022
  • 1 location
Imaging Versus Cardiac Biomarker Monitored HER2 Directed Therapy in Patients With Breast Cancer (HER2BIC)

Due to a risk of heart failure during HER2 directed therapy in breast cancer, treatment is monitored with imaging of myocardial function, which is resource demanding for both patients and the health care system. The purpose of this study is to evaluate, if biomarkers can replace imaging based examinations of …

  • 0 views
  • 14 Jun, 2022
  • 1 location
Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis (TETON)

Study RIN-PF-301 is designed to evaluate the safety and efficacy of inhaled treprostinil in subjects with idiopathic pulmonary fibrosis (IPF) over a 52-week period.

pulmonary fibrosis
nintedanib
idiopathic pulmonary fibrosis
lung biopsy
fibrosis
  • 9 views
  • 15 Jun, 2022
  • 39 locations
Cannabidiol in Patients With COVID-19 and Cardiovascular Disease or Risk Factors

Non-critical patients, hospitalized within the previous 24 hours who tested positive for COVID-19 and have a prior history of cardiovascular disease (CVD) and/or significant risk factors for CVD will be treated for 28 days.

diabetes
hypertension
  • 0 views
  • 03 May, 2022
  • 5 locations
Polypill Strategy for Heart Failure With Reduced Ejection Fraction

Heart failure with a reduced ejection fraction (HFrEF) represents a significant public health burden in the United States, with a growing prevalence particularly among African Americans and Hispanic Americans and individuals of low socioeconomic status (SES). Although effective therapies exist, gaps in their uptake contribute substantially to the excess burden …

medical therapy
metoprolol
spironolactone
ejection fraction
heart failure
  • 0 views
  • 21 Mar, 2022
  • 1 location