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Found 92 clinical trials
An Open-Label Study of Apabetalone in Covid Infection

The primary objective of the study is to evaluate the safety and effect on clinical course of oral apabetalone in hospitalized subjects with Covid-19 infection

  • 4 views
  • 22 Mar, 2022
  • 1 location
Clinical Experimentation With Tenofovir Disoproxyl Fumarate and Emtricitabine for COVID-19

Clinical, control, double-blind, randomized trial with tenofovir disoproxyl fumarate and emtricitabine for Covid-19

  • 0 views
  • 01 Feb, 2021
  • 1 location
Study of Cardiac MRI in the Follow up Assessment of Patients With PAH (EVITA)

Pulmonary arterial hypertension (PAH) is characterized by a progressive increase in pulmonary vascular resistance leading to right ventricular failure and eventually to death. The therapeutic strategy has become complex and needs to perform recurring follow up evaluations including right heart catheterizations (RHC). Cardiac magnetic resonance imaging (cMRI) has the advantage …

  • 0 views
  • 10 May, 2021
  • 1 location
Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCC (PARACHUTE-HF)

hierarchical composite of cardiovascular (CV) events (i.e. CV death or the occurrence of first HF hospitalization) and causing a greater reduction in n terminal prohormone of brain natriuretic peptide (NT

nesiritide
ventricular angiography
ejection fraction
nt-probnp
valsartan
  • 0 views
  • 01 Mar, 2022
  • 44 locations
Asian Diabetes Outcomes Prevention Trial (ADOPT)

The aim of this study is to identify patients with DM at high risk of CVD using elevated N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels (>125pg/mL), and (2) intensify therapy

cardiovascular disease
stroke
primary prevention
heart failure
stenosis
  • 148 views
  • 27 Feb, 2022
  • 1 location
Effectiveness of CRD-740 in Heart Failure (CARDINAL-HF)

whether CRD-740 reduces NT-proBNP compared to placebo at Week 12.

  • 0 views
  • 15 Jun, 2022
REmote iSchemic condItioning in Lymphoma PatIents REceiving ANthraCyclinEs (RESILIENCE)

Multinational, prospective, proof of concept phase II, double-blinded, sham-controlled, randomized clinical trial (RCT) to evaluate the efficacy and safety of Remote Ischaemic PreConditioning (RIPC) in Non-Hodgkin lymphoma (NHL) patients receiving anthracyclines.

  • 0 views
  • 15 Mar, 2022
  • 2 locations
A Phase 3 Study of Zalunfiban in Subjects With ST-elevation MI (CELEBRATE)

This is a Phase 3 prospective, blinded, randomized, placebo controlled, international multicenter study. Subjects with STEMI will be enrolled in the ambulance if they meet all eligibility criteria. These subjects will be evaluated by (para)medics who transport the subjects to the participating hospitals in Europe and North America. Hospitals and …

chest pain
stemi
angiography
  • 0 views
  • 23 May, 2022
  • 13 locations
Randomized Study of Extended Treatment With Firibastat in Treatment-Resistant Hypertension (REFRESH)

This is a double-blind, placebo-controlled and open-label, multicenter efficacy and long-term safety study of firibastat (QGC001) 1000 mg (2500 mg tablets) administered po, QD, for up to 48 weeks in patients with difficult-to-treat/treatment-resistant HTN. Subjects will continue to take their chronic antihypertensive therapies (at least 2 classes of antihypertensive therapies) …

resistant hypertension
antihypertensive drugs
hypertension
blood pressure diastolic
  • 0 views
  • 28 Sep, 2021
  • 2 locations
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acute myeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop the growth of cancer cells, …

daunorubicin
cancer
mitoxantrone
gemtuzumab
cytarabine/daunorubicin
  • 141 views
  • 10 May, 2022
  • 98 locations