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Found 24 clinical trials
A Second Magnetic Resonance Guided Focused Ultrasound Thalamotomy for Essential Tremor

This study will be a single-centre, prospective, single-arm, open-label, 12-week pilot trial assessing the safety and preliminary efficacy of a second MR-guided focused ultrasound (MRgFUS) thalamotomy on the naïve brain hemisphere after 48 weeks or more of the first MRgFUS thalamotomy in patients with medication-refractory ET. This study will be …

thalamotomy
MRI
propranolol
primidone
  • 22 views
  • 29 May, 2022
  • 1 location
Optimal Antithrombotic Therapy for ACS Patients Concomitant With AF and Implanted With New-generation DES (OPTIMA-3, 4)

- cardiovascular), MI (fatal or non-fatal, Q-wave or non-Q-wave), unplanned revascularization (target or non-target vessel, target or non-target lesion), stent thrombosis (possible, probable, definite), stroke

ticagrelor
percutaneous coronary intervention
thrombosis
clopidogrel
infarct
  • 51 views
  • 03 May, 2022
  • 1 location
Safety and Efficacy of ASN-002 Combined With a Hedgehog Pathway Inhibitor

is to: Evaluate the efficacy of intralesional ASN-002 in non-target tumours when administered in combination with oral vismodegib in patients with BCCs. The exploratory

punch biopsy
platelet count
carcinoma
neutrophil count
vismodegib
  • 0 views
  • 25 Mar, 2022
  • 5 locations
Coronary Computed Tomography Angiography For Optimized Invasive Coronary examInation (CT-FOCI)

reduction in patient radiation exposure, procedure time, procedural utensils, and contrast use. Secondary endpoints is significant stenosis in the non-target vessel, only available in the

dapt
stable angina
angiography
angina pectoris
luminal
  • 0 views
  • 28 May, 2022
  • 1 location
Placement of Antibiotic Powder in Wounds During the Emergency Room (POWDER)

This is the first prospective controlled study to determine whether the topical application of vancomycin powder reduces infection-related complications when applied to open fracture injuries in the acute emergency department setting.

injuries
open fracture
  • 0 views
  • 14 Mar, 2022
Coronary Physiology and Its Relationship to Anatomy in Patients With Diabetes Mellitus

Comprehensive assessment of coronary physiology (fractional flow reserve (FFR), coronary flow reserve (CFR) and index of microcirculatory resistance (IMR)) in patients with diabetes mellitus and coronary artery disease (CAD).

diabetes mellitus
coronary artery stenosis
ischemia
angina pectoris
arterial disease
  • 52 views
  • 10 May, 2022
  • 1 location
Customized 3D Printed Oral Stents During Head and Neck Radiotherapy

This clinical trial studies the effect of customized 3 dimensional (3D) printed oral tents on patients with head and neck cancer who are receiving radiotherapy. Oral stents are made from the impression of patients' mouth and cover patients' teeth and gums during radiation therapy. A customized, 3D-printed oral stent may …

  • 0 views
  • 08 Nov, 2021
  • 4 locations
Anlotinib or Penpulimab in Combination With RAI for DTC

The purpose of this study is to assess the efficacy and safety of anlotinib in combination with I-131 in locally advanced/metastatic differentiated thyroid cancer. Anlotinib may stop the growth of tumor cells and improve iodine uptake.

tumor cells
ct scan
measurable disease
  • 0 views
  • 23 Mar, 2022
  • 1 location
A Study to EXhibit Percutaneous Coronary Artery Dilatation With Non-Slip Element Balloon (EXPANSE-PTCA)

The objective of this study is to evaluate safety and effectiveness of the Lacrosse NSE ALPHA coronary dilatation catheter during PCI in subjects with stenotic coronary arteries.

  • 0 views
  • 19 Jun, 2022
  • 10 locations
Clinical Study of Granulocyte Infusion for Advanced Cancer

Background & Rationale: For years, most tumor immunotherapy researches have focused on T cell and natural killer (NK) cell therapies, most of which involve amplification and modification of the patient's immune cells for reinfusion therapy. However, for the treatment of solid tumors, there is currently little breakthrough. Recently, researchers have …

cancer treatment
solid neoplasm
liver metastasis
serum bilirubin
measurable disease
  • 0 views
  • 23 Jan, 2021
  • 1 location