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Found 83 clinical trials
Sintilimab IBI305 Plus Chemotherapy (Pemetrexed + Cisplatin) for EGFRm + Locally Advanced or Metastasis Non-Squamous NSCLC Patients After EGFR-TKI Treatment Failure

The anti-tumor activity of anti-PD-1 therapy and VEGF inhibitor in TKI-resistant EGFR-mutated Chinese non-squamous NSCLC patients will be investigated in this clinical trial.

EGFR
metastasis
measurable disease
vegf inhibitor
pemetrexed
  • 3 views
  • 24 Jan, 2021
  • 1 location
  • 0 views
  • 01 Apr, 2021
  • 54 locations
A Study to Evaluate SHR-1210 in Combination With Famitinib Plus Chemotherapy in Subjects With NSCLC.

The study is being conducted to evaluate the efficacy and safety of SHR-1210 in combination with Famitinib plus chemotherapy in subjects with NSCLC.

  • 0 views
  • 22 Mar, 2021
  • 7 locations
ABC-lung: Atezolizumab Bevacizumab and Chemotherapy in EGFR-mutant Non-small Cell Lung Carcinoma

(Arm A) or atezolizumab, bevacizumab and pemetrexed (Arm B) in patients with stage IIIB-IV non-squamous non-small cell lung cancer (NSCLC) harbouring EGFR mutations after failure of standard EGFR

  • 42 views
  • 09 Mar, 2021
  • 22 locations
A Trial to Compare the Efficacy Safety Pharmacokinetics and Immunogenecity of HD204 to Avastin in Advanced Non-squamous Non-small Cell Lung Cancer Patients

In the SAMSON-2 study, the proposed biosimilar HD204 will be compared to its reference product EU-licensed Avastin. The aim of the study is to demonstrate equivalence of HD204 and EU-licensed Avastin in terms of efficacy, safety, pharmacokinetics and immunogenecity.

carboplatin
carboplatin/paclitaxel
cancer
non-squamous non-small cell lung cancer
lung carcinoma
  • 80 views
  • 30 Apr, 2021
  • 23 locations
Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer

studies to identify intermediate and high-risk stage I or Stage IIA patients with non-squamous NSCLC, is now available to all clinicians through a CLIA-certified laboratory. It is therefore now possible

neutrophil count
adjuvant chemotherapy
lung carcinoma
non-squamous non-small cell lung cancer
endobronchial ultrasound
  • 0 views
  • 26 Mar, 2021
  • 21 locations
Efficacy Comparison of Dostarlimab Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Participants With Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC)

participants with non-squamous NSCLC without a known sensitizing epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), or receptor tyrosine kinase-1 (ROS-1) mutation, BRAF V600E mutation

  • 0 views
  • 26 Apr, 2021
  • 31 locations
Efficacy and Safety of BCD-100 (Anti-PD-1) in Combination With Platinum-Based Chemotherapy as First Line Treatment in Patients With Advanced Non-Squamous NSCLC

combination with pemetrexed+cisplatin/carboplatin in subjects with previously untreated metastatic non-squamous NSCLC. The main hypothesis of the study is that BCD-100 in combination with chemotherapy

  • 0 views
  • 25 Jan, 2021
  • 36 locations
A Study to Test Different Doses of BI 836880 Combined With BI 754091 in Patients With Advanced Non-small Cell Lung Cancer Followed by Other Types of Advanced Solid Tumours

This study has 2 parts. The first part is open to adults with advanced non-small cell lung cancer. The second part is open also to adults with other types of advanced cancer of the lung, brain, skin, and liver. The participants get a combination of two medicines called BI 836880 …

immunostimulants
advanced cancer
pembrolizumab
platinum-based chemotherapy
lung cancer
  • 17 views
  • 09 May, 2021
  • 62 locations
A Study to Evaluate Immunotherapy Combinations in Participants With Lung Cancer

etrumadenant (AB928) in combination with carboplatin and pemetrexed, with or without an anti-PD-1 antibody (pembrolizumab or zimberelimab), in participants with non-squamous Non-Small Cell Lung Cancer (NSCLC

carboplatin
pembrolizumab
growth factor
lung carcinoma
non-squamous non-small cell lung cancer
  • 74 views
  • 30 Jan, 2021
  • 79 locations