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Found 141 clinical trials
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High Flow Nasal Cannula With Noninvasive Ventilation

This is a prospective, randomized, unblinded trial of trauma patients in the ICU who are identified as being at a high risk to develop acute respiratory failure. We hope that this study will help the study team to identify how best to use a more aggressive respiratory treatment strategy in …

  • 0 views
  • 27 Jan, 2021
  • 1 location
None
NCPAP+MISA vs. NIPPV+MISA to NRDS a Multicenter Randomized Study

BACKGROUND Treatment of neonatal respiratory distress syndrome(NRDS) with exogenous surfactant and mechanical ventilation made millions of preterm infants survived in neonatal intensive care unit (NICU). Endotracheal intubation surfactant administration is related to invasive intubation and short periods of positive pressure ventilation and implies the risk of lung injury.Recent studies have …

  • 0 views
  • 03 Dec, 2021
  • 1 location
None
NHFOV vs NIPPV vs nCPAP in Preterm Infants With Respiratory Distress Syndrome

birth weight of less than 1500g when used as a primary noninvasive ventilation (NIV) mode.

  • 0 views
  • 26 Jan, 2021
  • 8 locations
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Spontaneous Breathing Trial With T-piece or Inspiratory Pressure Augmentation

after extubation and this may increase the use of noninvasive ventilation after extubation. An SBT with inspiratory pressure augmentation increases iMV free days but not MV free days as compared with T

  • 0 views
  • 06 Mar, 2021
  • 2 locations
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LYT-100 in Post-acute COVID-19 Respiratory Disease

This study is being conducted in two parts, A and B. Part A is a randomized, double-blind, parallel arm study to evaluate the safety and efficacy of LYT-100 compared to placebo in adults with post-acute COVID-19 respiratory complications. Part B is an Open Label Extension (OLE) study for patients who …

  • 10 views
  • 05 Aug, 2021
  • 23 locations
None
Phase IIb Trial of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) (Ad5-nCoV) in Adults 18 Years of Age and Older.

A randomized, double-blind, placebo -controlled, phase IIb clinical trial to evaluate the efficacy, safety and immunogenicity of one or two doses of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) in adults 18 years of age and older, living with HIV, on stable treatment, and virologically suppressed for at least …

  • 0 views
  • 01 Oct, 2021
  • 4 locations
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Speeding the Weaning up: Aggressive Screening Criteria and Higher Minimal Ventilatory Settings.

Hypothesis In patients with less than 4 high risk factors for reintubation excluding body mass index >30 and hypercapnia during the spontaneous breathing trial (SBT) (low and intermediate risk for extubation failure), who receive preventive therapy with high flow nasal cannula (HFNC), the use of SBT with "HIGH minimal ventilator …

  • 0 views
  • 03 May, 2021
  • 1 location
None
Noninvasive Ventilation for Chronic Heart Failure

reported. This project aims to clarify the efficacy and safety of home non-invasive ventilation in patients with chronic heart failure complicated with sleep-disordered breathing. First, patients with

  • 0 views
  • 12 Sep, 2021
  • 3 locations
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Non-Invasive Ventilation in Amyotrophic Lateral Sclerosis

Non-invasive mechanical ventilation (NIV) has been increasingly used as a treatment of chronic hypercapnic respiratory failure. Its use in patients affected by chronic obstructive pulmonary disorders is still controversial, while most of the studies performed in restrictive thoracic disorders (RTD), and in particular in neuromuscular patients, suggested alleviation of the …

non-invasive ventilation
maximal inspiratory pressure
respiratory failure
assisted ventilation
chronic hypoventilation
  • 49 views
  • 07 Nov, 2020
  • 1 location
None
Work of Breathing in Bronchiolitis Under Non-invasive Ventilation

Severe acute viral bronchiolitis is the leading cause of pediatric intensive care admission. The first-line recommended ventilation support is continuous positive airway pressure (CPAP), which reduces the work of breathing (WOB) and improves gas exchange. Although Non invasive Positive Pressure Ventilation (NiPPV) is increasingly used in case of CPAP failure …

  • 0 views
  • 26 May, 2021
  • 1 location