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Found 9 clinical trials
Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)

purpose of this study to evaluate the therapeutic response (combined microbiological and clinical efficacy per participant) of oral gepotidacin compared to oral nitrofurantoin for acute cystitis in

cystitis
dysuria
leukocyte esterase
nitrofurantoin
nitrite
  • 394 views
  • 26 Jan, 2021
  • 99 locations
A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)

This study will be conducted to evaluate the therapeutic response of oral gepotidacin compared to oral nitrofurantoin for uncomplicated UTI in adolescent and adult female subjects. In this study

cystitis
dysuria
leukocyte esterase
nitrofurantoin
nitrite
  • 671 views
  • 27 Jan, 2021
  • 79 locations
KRT-232 in Subjects With PMF Post-PV MF or Post-ET MF Who Have Failed a JAK Inhibitor

This study evaluates the efficacy in achieving clinical cure in non-bacteremic urinary tract infections (UTI) caused by Escherichia coli or Klebsiella pneumoniae producers of extended-spectrum -lactamases (ESBL) in adult patients. Half of participants will receive Piperacillin/Tazobactam as treatment, while the other half will receive Carbapenems. The investigators will verify that …

  • 134 views
  • 23 Jan, 2021
  • 90 locations
Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery

We aim to compare the effectiveness of cranberry capsules versus nitrofurantoin prophylaxis in preventing urinary tract infections (UTIs) after urogynecologic surgery by conducting a double

cranberry extract
nitrofurantoin
incontinence
brimonidine tartrate ophthalmic solution
urinary tract infection
  • 10 views
  • 26 Jan, 2021
Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy

or nitrofurantoin may prevent or control infections in patients with urinary tract infection and may help improve their response to radical cystectomy. Information gained from this study may help

sulfamethoxazole
nitrofurantoin
invasive bladder cancer
antibiotics
antibiotic therapy
  • 0 views
  • 24 Jan, 2021
  • 1 location
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2

This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy. The select patient population will be those patients deemed to be at a moderately increased risk of postoperative infectious complications. These higher risk …

ampicillin
nitrofurantoin
gentamicin
nephrolithotomy
antibiotics
  • 35 views
  • 24 Jan, 2021
  • 1 location
Nutraceutical Efficacy for rUTI

This is a study designed to evaluate the efficacy of a nutraceutical as a non-antibiotic treatment to prevent recurrent urinary tract infections in women that have completed menopause and are on vaginal estrogen therapy. An additional group of women with recurrent urinary tract infections that have completed menopause but are …

recurrent urinary tract infection
antibiotic therapy
antibiotics
  • 106 views
  • 24 Jan, 2021
  • 1 location
Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic UTI Due to -ESBL-producing Enterobacteriaceae

This study evaluates the efficacy in achieving clinical cure in non-bacteremic urinary tract infections (UTI) caused by Escherichia coli or Klebsiella pneumoniae producers of extended-spectrum -lactamases (ESBL) in adult patients. Half of participants will receive Piperacillin/Tazobactam as treatment, while the other half will receive Carbapenems. The investigators will verify that …

carbapenem
fever
antibiotics
dysuria
antibiotic therapy
  • 23 views
  • 23 Jan, 2021
  • 2 locations
Missing Microbes in Infants Born by Cesarean Section

General adult healthy pregnant females in total 400, as well as their infants will be recruited. It is expected 67% will be vaginally delivered and 33% will be C Section deliveries. It is expected that of these groups that 40% of these women will be treated with antibiotics during their …

  • 0 views
  • 23 Jan, 2021
  • 1 location