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Found 7 clinical trials
Safety, Tolerability, Pharmacokinetic and Microbiological Investigation of GSK3882347 in Female Participants With Urinary Tract Infections

This phase 1b study is a double-blind, double-dummy, nitrofurantoin-controlled study designed to evaluate microbiological response at the test of cure (ToC) visit along with safety, tolerability

  • 0 views
  • 07 Oct, 2022
  • 3 locations
Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)

The study will be conducted to evaluate the therapeutic response (combined per participant microbiological and clinical response) of oral gepotidacin compared to oral nitrofurantoin for

dysuria
cystitis
gepotidacin
acute cystitis
leukocyte esterase
  • 607 views
  • 07 Jul, 2022
  • 111 locations
A Phase III, Randomized, Multicenter, Parallel-Group, Double-Blind, Double-Dummy Study in Adolescent and Adult Female Participants Comparing the Efficacy and Safety of Gepotidacin to Nitrofurantoin in the Treatment of Uncomplicated Urinary Tract Infection (Acute Cystitis)

The study will be conducted to evaluate the therapeutic response (combined per participant microbiological and clinical response) of oral gepotidacin compared to oral nitrofurantoin for

dysuria
cystitis
gepotidacin
acute cystitis
leukocyte esterase
  • 774 views
  • 13 Oct, 2022
  • 95 locations
Clinical Effectiveness and Bacteriological Eradication of 4 Short-course Antibiotics for Uncomplicated UTIs in Women. (SCOUT)

following four groups: 2-day 3 g fosfomycin o.d., 3-day pivmecillinam 400 mg. t.i.d, 5-day nitrofurantoin 100 mg t.i.d. or a single dose of 3 g of fosfomycin. Sample: 1,000 patients. Two co-primary

antibiotics
nitrofurantoin
pivmecillinam
tenderness
dysuria
  • 7 views
  • 07 Oct, 2022
  • 8 locations
Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery

We aim to compare the effectiveness of cranberry capsules versus nitrofurantoin prophylaxis in preventing urinary tract infections (UTIs) after urogynecologic surgery by conducting a double

brimonidine tartrate ophthalmic solution
cranberry extract
incontinence
urinary tract infection
prolapse
  • 16 views
  • 04 Oct, 2022
  • 1 location
Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy

or nitrofurantoin may prevent or control infections in patients with urinary tract infection and may help improve their response to radical cystectomy. Information gained from this study may help

invasive bladder cancer
antibiotic therapy
antibiotics
trimethoprim-sulfamethoxazole
ertapenem
  • 0 views
  • 10 May, 2022
  • 1 location
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2 (PNLABXPART2)

This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy. The select patient population will be those patients deemed to be at a moderately increased risk of postoperative infectious complications. These higher risk …

endourology
antibiotic therapy
percutaneous nephrolithotomy
antibiotics
nephrostomy
  • 35 views
  • 24 Feb, 2022
  • 1 location