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Found 25 clinical trials
Nitrate and Power Output After Two Beetroot Juice Drinks

The main aim of this study is to determine and compare the optimal time to achieve peak concentration of blood plasma nitrite after ingestion of beetroot juice (BR) and isotonic beetroot juice

Accepts healthy volunteers
  • 0 views
  • 21 Jul, 2022
Study of SIAN Nasal Spray in Healthy Adults

This study is designed to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses of Stabilized Isoamyl Nitrite (SIAN) nasal spray in healthy

Accepts healthy volunteers
  • 0 views
  • 06 May, 2022
  • 1 location
Use of 2-Octyl Cyanoacrylate (Dermabond) in Neonatal Circumcision: A Randomized Controlled Trial

circumcision within 180 days with the following complication in specific or in composite Bleeding requiring hemostatic intervention (suturing, dermabond application, silver nitrite application, pressure

  • 0 views
  • 22 Oct, 2021
  • 1 location
HIgh Flow Versus NIV for Acute Cardiogenic PuLmonary Oedema With Acute Respiratory Failure in an ED

The purpose of this study is to compare non invasive ventilation to high flow nasal cannula oxygen for the management of patients admitted with an acute respiratory failure due to an acute cardiogenic pulmonary edema.

  • 0 views
  • 07 Oct, 2021
  • 1 location
Use of Beetroot Juice to Protect Against Postoperative Ileus Following Colorectal Surgery: BEET IT Study

The goal of the BEET IT study is to examine if preoperative intake of beetroot juice can ameliorate gastrointestinal (GI) recovery after colorectal surgery and thereby help to reduce the duration of postoperative ileus (POI). Adult patients undergoing laparoscopic colorectal surgery are randomized 1:1 to consume either concentrated beetroot juice …

  • 3 views
  • 01 Dec, 2021
  • 4 locations
Effect of Antibacterial Mouthwash on Muscle Function in Healthy Young Men and Women

The purpose of this study is to determine the effects of antibacterial mouthwash on muscle speed and power in healthy young men and women. We have previously demonstrated that drinking beetroot juice, a source of dietary nitrate and therefore nitric oxide, increases muscle function in this population. Antibacterial mouthwash has …

Accepts healthy volunteers
  • 0 views
  • 25 May, 2022
  • 1 location
Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers

The investigators propose a Phase II study, prospective and placebo controlled, of a topical cream containing sodium nitrite compared to the current standard of care. Sodium nitrite is a local

nitrite
leg ulcer
thalassemia
nitric oxide
  • 33 views
  • 26 Apr, 2022
  • 2 locations
Nitrite-boosting Therapy for Improving Physiological Function in Patients With Chronic Kidney Disease

Nitric oxide (NO) is an essential molecule in the body that is decreased in patients with chronic kidney disease (CKD), leading to reductions in vascular, movement ("motor") and cognitive functions. This study will determine if daily oral supplementation (3 months) with a supplement that increases NO in the body, i.e., …

nephropathy
renal function study
  • 7 views
  • 09 Feb, 2022
  • 1 location
Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age (Nitrite)

This 2-site randomized double blinded controlled trial is to confirm and more definitively clarify the impact of a 12-week course of nitrite versus placebo on mitochondrial bioenergetics in

  • 0 views
  • 17 Jun, 2022
  • 1 location
The Causal Relation of Nasal Nitric Oxide Levels to the Severity of Chronic Rhinosinusitis and Its Inflammatory Phenotype

the relation of chronic rhino sinusitis (CRS) severity and inflammatory status to nNO, maxillary sinus NO, nitrite, nitrate and cone beam computed tomography (CBCT). Three groups (22 patients

nitrite
asthma
rhinosinusitis
ct scan
Accepts healthy volunteers
  • 0 views
  • 21 Mar, 2022
  • 1 location