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Found 28 clinical trials
Use of 2-Octyl Cyanoacrylate (Dermabond) in Neonatal Circumcision: A Randomized Controlled Trial

circumcision within 180 days with the following complication in specific or in composite Bleeding requiring hemostatic intervention (suturing, dermabond application, silver nitrite application, pressure

  • 0 views
  • 12 Jun, 2021
  • 1 location
Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers

The investigators propose a Phase II study, prospective and placebo controlled, of a topical cream containing sodium nitrite compared to the current standard of care. Sodium nitrite is a local

thalassemia
leg ulcer
nitrite
nitric oxide
  • 23 views
  • 27 Jan, 2021
  • 2 locations
Oral Nitrite in Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction

The main objective of this study is to determine the clinical efficacy of oral inorganic nitrite verses placebo and the therapeutic response with regards to exercise tolerance in patients with

heart failure with preserved ejection fraction
ejection fraction
  • 1 views
  • 18 Mar, 2021
  • 2 locations
Nitrite-boosting Therapy for Improving Physiological Function in Patients With Chronic Kidney Disease

Nitric oxide (NO) is an essential molecule in the body that is decreased in patients with chronic kidney disease (CKD), leading to reductions in vascular, movement ("motor") and cognitive functions. This study will determine if daily oral supplementation (3 months) with a supplement that increases NO in the body, i.e., …

nephropathy
renal function study
  • 7 views
  • 07 May, 2021
  • 1 location
Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction (HFpEF) (INABLE-Training)

Participants with heart failure with preserved ejection fraction will undergo 12 weeks of cardiac rehabilitation for exercise training (ET) and be randomized to either oral sodium nitrite

diastolic dysfunction
dyspnea
heart failure
edema
nesiritide
  • 0 views
  • 14 Mar, 2021
  • 1 location
Nitrites Skeletal Muscle Mitochondrial Bioenergetics and Physical Activity in Old Age

This 2-site randomized double blinded controlled trial is to confirm and more definitively clarify the impact of a 12-week course of nitrite versus placebo on mitochondrial bioenergetics in

  • 0 views
  • 08 May, 2021
  • 1 location
The Causal Relation of Nasal Nitric Oxide Levels to the Severity of Chronic Rhinosinusitis and Its Inflammatory Phenotype

the relation of chronic rhino sinusitis (CRS) severity and inflammatory status to nNO, maxillary sinus NO, nitrite, nitrate and cone beam computed tomography (CBCT). Three groups (22 patients

asthma
nitrite
ct scan
rhinosinusitis
  • 0 views
  • 24 Jan, 2021
  • 1 location
The Effect of Propolis Mouthwash Compared to Chlorhexidine Mouthwash on Oral and Cardiovascular Health

The oral microbiome has recently emerged as a key contributor in nitric oxide (NO) homeostasis and vascular control by increasing nitrite bioavailability. Antibacterial mouthwash containing

  • 0 views
  • 26 Jan, 2021
  • 1 location
Influence of Freeze Dried Strawberry Consumption on Gut Microbiota and Cardiovascular Health.

the influence of the FDSP on circulating levels of nitrate and nitrite and trimethylamine oxide (TMAO) as markers of vascular health that are influenced by both dietary intake and the oral and gut

  • 108 views
  • 10 Jun, 2021
  • 1 location
Investigation of the Effects of Dietary Nitrate and Sex on COVID-19 Vaccine Induced Vascular Dysfunction in Healthy Men and Women (DiNOVasc-COVID-19)

raise circulating plasma nitrite levels and thereby prevent the systemic inflammation that causes vascular dysfunction.

  • 0 views
  • 24 May, 2021
  • 1 location