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Found 181 clinical trials
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Role of Genetic Factors in the Pathogenesis of Lung Disease

This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. The study will focus on defining the distribution of abnormal genes responsible for processes …

pulmonary disease
pulmonary fibrosis
bronchoscopy
diabetes
  • 120 views
  • 23 Nov, 2020
  • 1 location
Albumin Replacement Therapy in Septic Shock

endogenous molecules, anti-inflammatory and anti-oxidant actions, nitric oxide modulation, and buffer function. The accumulating evidence suggests that supplementation of albumin may provide survival

buffers
resuscitation
sepsis
lactate level
lactic acid
  • 15 views
  • 24 Jan, 2021
  • 5 locations
Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)

Combination therapy in pulmonary arterial hypertension (PAH) has been the subject of active investigation for more than a decade, with the benefit of targeting different pathways known to be involved in the pathogenesis of the disease. Adherence to prescribed therapy has an impact on clinical outcomes. Reducing the pill/tablet count …

  • 100 views
  • 01 Jan, 2021
  • 204 locations
A Monocentric Study Assessing the Efficacy of the Nitrosylated Hemoglobin as Biomarker for Detecting the Development of a Cardiovascular Complication During or After Surgery

Cardiovascular diseases are the first mortality cause in Occidental countries. Surgery and anesthesia can provoke hemodynamic instability and stimulation of the sympathetic nervous system as well as bleeding or thrombosis. These factors as top of some post-operative factors such as tissular hypoxemia, can result in cardiovascular complications. Developing a tool …

cardiovascular disease
diabetes
  • 0 views
  • 07 Oct, 2020
  • 1 location
Combined Air-plasma Flow and Nitric Oxide Therapy in Cardiac Surgery

complications is beyond doubt. In this study, it is supposed to examine and evaluate the effectiveness of the combined effects of air-plasma flow and nitric oxide in the treatment of postoperative infectious

  • 0 views
  • 16 Nov, 2020
  • 1 location
The Effect of Inhaled Nitric Oxide on Maximal Oxygen Consumption During Exercise in Hypoxia

effects of hypoxia. It appears that this blood vessel constriction may limit the heart to pump blood during heavy exercise, leading to reductions in exercise performance. Inhaled nitric oxide is a drug

  • 0 views
  • 24 Jan, 2021
  • 1 location
Nitric Oxide Inhalation Therapy for COVID-19 Infections in the ED

requiring ICU admission and ventilatory support. While COVID-19 patients have an increased need for supportive care, there is currently no specific treatment directed against 2019-nCoV. Nitric oxide

cough
oximetry
antiviral drugs
nitric oxide
respiratory symptom
  • 0 views
  • 24 Jan, 2021
Study of Arginine Metabolism and Nitric Oxide Formation in Relation to Glutamine Supply in Severely Burned Patients

The purpose of the study is to understand the way the body uses amino acids and proteins in burned patient during the time they cannot eat normally. This study aims to understand the metabolism of the amino acid arginine in the body after burn injury. The results of this study …

amino acids
inhalation injury
glutamine
basal metabolic rate
  • 5 views
  • 07 Nov, 2020
  • 1 location
Development of a New Method for Steady-State Measurement of NO Lung Diffusing Capacity in Healthy Subjects

Using a rapidly responding nitric oxide analyzer in a new developed modular lung-function-setup we are going to measure steady-state NO diffusing capacity in 107 healthy subjects (age 6

  • 4 views
  • 07 Nov, 2020
  • 1 location
Herbal Supplement Prosta-OK Neo as an Adjunct Therapy in Patients With Mild to Severe Non-neurogenic Male Lower Urinary Tract Symptoms Receiving Tamsulosin Therapy

functions of inhibiting 5-alpha reductase, antioxidant, anti-inflammation and regulating the synthesis of nitric oxide to explore whether Prosta-OK can help reduce symptoms and elevate the quality of life

tamsulosin
zinc
nitric oxide
lycopene
pumpkin seed
  • 0 views
  • 25 Jan, 2021
  • 1 location