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Found 104 clinical trials
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Biology and Genetics of Human Brain Arteriovenous Malformations

Patients eligible for enrollment in this study will be from the Northwell Neurosurgery practice. We propose to enroll an initial set of 10 BAVM patients and 10 epilepsy patients in the

  • 64 views
  • 12 Aug, 2020
  • 1 location
Durability of Double-gloving With Biogel Surgical Gloves When Used by Clinicians/Surgeons

A prospective open-label study design was chosen because it will provide the most accurate data on the efficacy of four commercially available similar brands of NRL (natural rubber latex) and synthetic latex surgical gloves when they are used for surgeries in a clinical setting. The primary endpoint will be the …

  • 1 views
  • 25 Jan, 2021
  • 1 location
MusiC to Prevent deliriUm During neuroSurgerY

Rationale: Delirium is a common and severe complication after neurosurgical procedures. Music before, during and after surgical procedures has proven its effectiveness in reducing pain, anxiety, stress and opioid medication in surgical patients. These symptoms belong to the main eliciting factors for developing delirium. Effective preventive therapy for delirium is …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Operative Procedures vs. Endovascular Neurosurgery for Untreated Pseudotumor Trial

Pseudotumor cerebri, also called idiopathic intracranial hypertension (IIH), is characterized by elevated intracranial pressure, headache, and if severe, vision loss. IIH is difficult to treat. Medical management may not adequately resolve the symptoms, and surgical management (primarily through cerebrospinal fluid [CSF] shunting) has a high failure rate. Recently, a relationship …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies

Microdialysis permits sampling of molecules from the extracellular fluid, and has been utilized for studies of pharmacokinetics, and recovery of biomarkers. Gliomas remain incurable--in part due to limited access to human tumor biology in available preclinical models. This study utilizes a variable rate pump (M dialysis 107) and a high …

  • 0 views
  • 09 Mar, 2021
  • 1 location
Improving Tumor Treating Fields Treatment for Brain Cancer Patients With Skullremodeling Surgery (Neurosurgery)

The aim of this trial is to test a new potential treatment, skullremodeling surgery (SR-surgery) combined with tumor treating fields (TTFields), for patients with first recurrence of malignant brain tumor (first recurrence of glioblastoma). Glioblastoma is one of the most malignant cancers. TTFields is a new treatment for brain cancer …

  • 0 views
  • 26 Jan, 2021
  • 1 location
The Paediatric EVICEL Neuro Study

The purpose of this study is to evaluate the safety and efficacy of EVICEL when used for suture-line sealing in dura-mater closure in elective or urgent paediatric cranial neurosurgery to

  • 81 views
  • 10 Apr, 2021
  • 7 locations
Effects of Intravenous Anesthesia and Balanced Anesthesia on Flash Visual Evoked Potentials

Intraoperative flash visual evoked potentials (FVEPs) could monitor visual function during neurosurgery. There are fewer reports comparing the effects of sevoflurane-propofol balanced anesthesia

  • 0 views
  • 13 Mar, 2021
  • 1 location
Low Intracranial Pressure Treatment Strategies for Chronic Subdural Hematoma Patients

The proportion of the elderly population is increasing rapidly. Chronic subdural hematoma has become the most common cause of surgery in neurosurgery for elderly patients. The standard treatment

  • 0 views
  • 26 Jan, 2021
  • 1 location
Assessment of Venous Drainage in Idiopathic Intracranial Hypertension

symptoms are headaches, blindness, pulsatile tinnitus or papillary edema. There are many options for the treatment of IIH, especially neurosurgery (derivation of cerebrospinal fluid or stent placement

  • 0 views
  • 24 Jan, 2021
  • 1 location