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Found 48 clinical trials
Study on the Diagnostic Cut-off Value of Core Biomarkers in Cerebrospinal Fluid and Blood of Alzheimer's Disease

The participant in this study includes Alzheimer's disease (AD including familial AD and sporadic AD) patients, amnestic mild cognitive impairment (aMCI) patients, non-AD dementia patients and cognitively normal control. The purpose of this study is to establish the best cut-off value of cerebrospinal fluid (CSF) and blood β-amyloid (Aβ) 42/40, …

alzheimer's disease
dementia
mild cognitive impairment
cognitive impairment
amyloid
  • 28 views
  • 16 Oct, 2022
  • 1 location
Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS-ND)

This is a 5-year observational study recruiting sixteen hundred and fifty individuals between the ages of 50 and 90 with different types of dementia as well as a comparison group of six hundred and fifty aged matched individuals without cognitive deficits. Participants will be recruited at sites across Canada and …

cognitive assessment
Accepts healthy volunteers
dementia
cognitive impairment
cognitive disorder
  • 616 views
  • 23 Feb, 2022
  • 25 locations
Study on Biomarkers for Early Diagnosis of Alzheimer's Disease

The project of Bio-AD is a population- based cohort study among the elderly in China. The project includes not only Alzheimer's disease (AD including familial AD and sporadic AD), but also other clinical stage of AD, as well as elderly people with normal cognitive function. The project will collect, detect …

alzheimer's disease
mini-mental state examination
cognitive impairment
mild cognitive impairment
amyloid
  • 0 views
  • 24 Jan, 2022
  • 1 location
Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

This is a research study that aims to examine whether Veterans with mild Traumatic Brain Injuries are at risk for dementia by studying their memory, brain wave activity, brain structure and proteins that can be elevated after brain injury and in dementia.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Tennessee Alzheimer's Project (TAP)

The primary objective of the Vanderbilt Alzheimer's Disease Research Center (VADRC) is to provide local and national researchers with access to a well-characterized and diverse clinical cohort, including participant referrals, biosamples, clinical data, and neuroimaging data. The VADRC Clinical Core will create an infrastructure to support research efforts of both …

Accepts healthy volunteers
alzheimer's disease
cognitive impairment
mild cognitive impairment
  • 5 views
  • 09 Jun, 2022
  • 1 location
Cerebellar Mutism Syndrome Study

The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS). Furthermore the purpose is to explore the clinical course and the best treatment of the syndrome.

  • 14 views
  • 28 Jan, 2021
  • 28 locations
  • 0 views
  • 04 Oct, 2022
  • 6 locations
PRedicting the EVolution of SubjectIvE Cognitive Decline to Alzheimer's Disease With Machine Learning (PREVIEW)

. The aim of this study is to evaluate, through machine learning tools, the accuracy data, neuropsychological assessment, personality traits, cognitive reserve, genetic factors, cerebrospinal

alzheimer's disease
mini-mental state examination
dementia
mild cognitive impairment
depression
  • 0 views
  • 23 Oct, 2022
  • 4 locations
Links Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease. (Drépa-COG)

times, cognitive impairments and cerebral disorders are not diagnosed and treated in adults with SCD. The main objective of this study is to propose a deep neuropsychological assessment in adults

vaso-occlusive crisis
chest syndrome
transcranial doppler ultrasonography
acute chest syndrome
blood disorder
  • 0 views
  • 06 Apr, 2022
  • 1 location
Brain Structure and Neurocognitive Development in Sickle Cell Disease; a Longitudinal Cohort Study (BRICK Study) (BRICK)

examination, neuropsychological assessment and blood sampling three times in total, with intervals of two years; results will be innovatively compared with children included in the Generation R population

cell transplantation
blood disorder
  • 0 views
  • 22 Oct, 2022
  • 1 location