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Found 48 clinical trials
The Effects of Transcranial Direct Current Stimulation (tDCS) and Cognitive Training in Patients With TBI

Long-term sequelae in TBI is a well-recognized burn. We designed a proof of concept study, randomized, double-blind, placebo-controlled to evaluate 36 adult TBI patients. To evaluate the early and late effects of 10 days of 20 minutes applying transcranial direct-current stimulation (tDCS) in the dorsolateral prefrontal cortex (DLPFC), bilateral temporal …

cognitive training
traumatic brain injury
  • 32 views
  • 25 Jan, 2021
  • 1 location
Technology-assisted Conscientiousness Therapy for People With Multiple Sclerosis (TACT-MS)

This is a validation study of a conscientiousness-based phone app intervention strategy to help people with their health management and employment.

  • 0 views
  • 11 Mar, 2022
  • 1 location
Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Disease Using the PET Ligand PI-2620

The investigators will compare PI-2620 tau PET scans from patients with frontotemporal lobar degeneration (FTLD), patients with non-amnestic presentations of Alzheimer's disease (naAD), and demographically matched cognitively normal seniors.

Accepts healthy volunteers
alzheimer's disease
  • 0 views
  • 24 Oct, 2022
  • 1 location
Mitochondrial Stress, Brain Imaging, and Epigenetics (MiSBIE)

The MiSBIE study collects biological, behavioral, psychosocial, neuropsychological, and brain imaging data in participants with either: normal mitochondrial function, individuals with the m.3243A>G mitochondrial DNA (mtDNA) mutation, and individuals a single large-scale mtDNA deletion. These defects induce mitochondrial allostatic load (MAL). The 2-day protocol, plus home-based data collection, will provide …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Intervention Effect of High Definition Transcranial Direct Current Stimulation (HD-tDCS) on Anxiety Disorder

To investigate the intervention effect of high definition transcranial direct current stimulation (HD-tDCS) on anxiety symptoms and somatic symptoms in patients with anxiety disorder and its underlying neural mechanism by MRI.

  • 0 views
  • 20 Apr, 2022
  • 1 location
Mindfulness-Based Stress Reduction to Improve Neuropsychological Functioning in Acquired Brain Injury

Thousands of Veterans suffer a stroke every year, and these individuals often suffer emotional and cognitive changes that negatively affect their quality of life as well as their ability to recover. In addition to traditional rehabilitation such as physical and occupational therapy, a number of alternative treatments are now being …

aphasia
movement therapy
  • 2 views
  • 09 Apr, 2022
  • 1 location
Understanding the Effects of Listening Effort on Sentence Processing and Memory in Sensorineural Hearing Loss: Evidence From Simultaneous Electrophysiology and Pupillometry (Study 1)

Sensorineural hearing loss (SNHL) is among the most prevalent chronic conditions in aging and has a profoundly negative effect on speech comprehension, leading to increased social isolation, reduced quality of life, and increased risk for the development of dementia in older adulthood. Typical audiological tests and interventions, which focus on …

Accepts healthy volunteers
  • 0 views
  • 25 Oct, 2022
  • 1 location
Applying Non-invasive Brain Stimulation in Alzheimer's Rehabilitation (StimoLaMente)

Presently, few studies have evaluated the clinical impact of rTMS in Alzheimer's disease. Though some studies have demonstrated an improvement, there have been conflicting results, as others do not seem to demonstrate beneficial effects. Furthermore, it is the combined application of rTMS with cognitive training that could represent a real …

alzheimer's disease
cholinesterase inhibitors
mental state examination
mini-mental state examination
cognitive impairment
  • 0 views
  • 06 Jun, 2022
  • 1 location
Brain Tissue Integrity and Autonomic Function Alterations in Childhood OSA and ADHD and After Adenotonsillectomy.

Obstructive sleep apnea (OSA) and attention-deficit/hyperactivity disorder (ADHD) are two common, severe disorders in children. Unfortunately, pediatric OSA is closely associated with ADHD, and both diseases can cause cognitive impairment, behavior problems, and low academic performance. OSA can damage the brain and induce autonomic dysfunction, and then cause cognitive, behavioral, …

  • 0 views
  • 05 Feb, 2021
  • 1 location
Vanderbilt Memory and Aging Project (VMAP)

This study will use an observational cohort to cross-sectionally and longitudinally relate vascular health to clinical, imaging, and biological markers of early Alzheimer's disease and cerebrovascular disease among aging adults. Adjusting for relevant clinical covariates, we will test the hypothesis that vascular health is associated with clinical, brain magnetic resonance …

alzheimer's disease
cognitive impairment
cognitive decline
mild cognitive impairment
dementia
  • 18 views
  • 27 May, 2022
  • 1 location