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Found 39 clinical trials
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A Double-Blind, Placebo-Controlled 16-Week Study of the Cognitive Effects of the Oral P38 Alpha Kinase Inhibitor Neflamapimod in Dementia with Lewy Bodies (DLB)

The primary objective is to evaluate the effect of neflamapimod on cognitive function as assessed in a study-specific Neuropsychological Test Battery

neuropsychological test
cholinesterase
  • 18 views
  • 08 Dec, 2020
  • 1 location
Preoperative Vitamin B12 and Folic Acid on POCD in Elderly Non-cardiac Surgical Patients

days before surgery. Neuropsychological test battery (NPB) will be tested before intervention and at discharge for determination of Post operative cognitive dysfunction (POCD). Another group of non

  • 0 views
  • 25 Jan, 2021
  • 13 locations
Effects of Different Types of General Anesthesia on Postoperative Pupillary Reactivity

Objective: To compare the effects of volatile and intravenous anesthetics on pupillary function after general anesthesia using a portable infrared pupillometer. Design: A monocentric, prospective, double blinded randomized study. Patients: Patients who require elective Ear, Nose and Throat (ENT) surgery under general anesthesia. Interventions: Patients undergoing elective ENT surgery will …

  • 1 views
  • 01 May, 2021
  • 1 location
Serotonergic Modulation of Cognition Emotion and Brain Activation in Healthy Volunteers

The aim of this project is: To apply a pharmacological tool of selective serotonin (5-hydroxytryptamine, 5-HT system) reuptake inhibition in healthy humans. Specifically: To investigate how sub-chronic administration of 20 mg of escitalopram affects cognitive performance ('cold' cognition) and social-emotional functioning ('hot' cognition) compared with placebo; and To investigate how …

  • 52 views
  • 25 Jan, 2021
  • 1 location
Crossover Study of Propranolol vs Ivabradine in POTS

1.0 BACKGROUND Postural tachycardia syndrome (POTS) is a disorder of chronic orthostatic intolerance characterized by symptoms of palpitations, lightheadedness, chest discomfort, shortness of breath, blurred vision, and mental clouding. These symptoms occur during standing and are associated with a marked increase in heart rate (HR) in the absence of hypotension, …

  • 0 views
  • 18 Mar, 2021
  • 1 location
Effects of Keppra on Thinking Emotions and Balance in Elderly Healthy Volunteers

Epilepsy is a common disorder with an incidence of about 6 per 1000. The incidence progressively increases above age 50. By age 75, the incidence is two to three fold compared with any age group. Unfortunately, older individuals are especially at risk to incur significant side effects to anti-epileptic drugs. …

neuropsychological test
seizure
keppra
anti-epileptic drug
levetiracetam
  • 4082 views
  • 07 Nov, 2020
  • 1 location
Cognitive Function Evaluation and Rehabilitation by a Digital Game: MentalPlus

Cognitive dysfunction is a frequent adverse event in the postoperative period, especially in elderly patients. The tests commonly used for the detection of postoperative cognitive dysfunction (POCD) are time-consuming what limits their routine use. Consequently; there is a limitation to adopt measures to increase preoperative cognitive reserve and rehabilitation of …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Psychometric Validation of the Competitive Attention Test

This project aims at validating a new neuropsychological test to measure voluntary and involuntary attention for clinical use to diagnose attentional deficits. This project proposes:

attention deficit disorder
hyperactivity
psychostimulants
neuropsychological test
psychiatric disorder
  • 62 views
  • 23 Jan, 2021
  • 1 location
Mixed Nuts and Brain Vascular Function

, and cognitive functioning as assessed with a neuropsychological test battery.

  • 3 views
  • 24 Jan, 2021
  • 1 location
GIST and Memory and Attention Adaptation Training

both self-reported cognitive impairments and objective neuropsychological test performance in GIST patients.

  • 0 views
  • 29 May, 2021
  • 1 location