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Found 209 clinical trials
Neuromodulation and Cognitive Training in Opioid Use Disorder

The relapsing nature of opioid use disorder is a major obstacle to successful treatment. About 90% of those entering treatment will relapse within one year. To improve treatment outcome, new interventions targeting the underlying brain biomarkers of relapse vulnerability hold significant promise in reducing this critical public health problem. Transcranial …

opioid use disorder
drug use
opioid use
substance use
mental illness
  • 120 views
  • 15 Feb, 2022
  • 1 location
Fluoroscopy Radiation Reduction During Sacral Neuromodulation Lead Placement

Fluoroscopy is performed when placing a lead during a sacral neuromodulation procedure. During lead placement, subjects will receive either conventional or experimental fluoroscopic settings

nocturia
neuromodulation
overactive bladder
urinary urgency
incontinence
  • 8 views
  • 21 Oct, 2021
  • 1 location
Effect of Peripheral Neuromodulation on Vaginal Blood Flow

The researchers want to see if nerve stimulation interventions cause a change in vaginal blood flow. The effect of this intervention will be compared between women who have neurogenic (spinal cord injury) or non-neurogenic dysfunction and healthy women.

spinal cord disorder
Accepts healthy volunteers
spinal cord
spinal injury
  • 84 views
  • 18 Nov, 2021
  • 1 location
Enhancing Acupuncture Treatment Effect Through Non-invasive Neuromodulation

In this study, investigators will examine the brain mechanism behind the synergistic effects of combining acupuncture and transcranial direct current stimulation (tDCS) treatments. Specifically, chronic low back pain (cLBP) patients will be recruited and randomized to one of four groups (30 per group, one month of treatment): 1) verum acupuncture …

  • 0 views
  • 28 Mar, 2021
  • 1 location
Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes

the autonomic nervous system works after spinal cord injury and if it's function can be improved utilizing neuromodulation.

neurologic findings
Accepts healthy volunteers
spinal injury
spinal cord stimulation
nervous
  • 0 views
  • 14 Mar, 2022
  • 1 location
Neuromodulation and Cognitive Training for Substance Use Disorders

The relapsing nature of substance use disorder is a major obstacle to successful treatment. About 70% of those entering treatment will relapse within one year. To improve treatment outcome, new interventions targeting the underlying brain biomarkers of relapse vulnerability hold significant promise in reducing this critical public health problem. This …

  • 6 views
  • 23 Jul, 2022
  • 1 location
Neuromodulation and Yoga for mTBI and Chronic Pain

The objectives of this VA SPiRE application are to develop a combined neuromodulation and yoga (iTBS+yoga) intervention for Veterans with mild traumatic brain injury (mTBI) and chronic pain

chronic pain
opioid
neuromodulation
  • 0 views
  • 13 May, 2022
  • 1 location
Treatment Evaluation of Neuromodulation for Tinnitus - Stage A3 (TENT-A3)

TENT-A3 is a single arm repeated measures prospective investigation evaluating the safety and efficacy of the Lenire device for tinnitus treatment. The Lenire device provides non-invasive bimodal (sound and tongue) stimulation to alleviate the symptoms of chronic, subjective tinnitus. Participants presenting to one of the several study sites with a …

audiogram
neuromodulation
  • 0 views
  • 04 Jun, 2022
  • 3 locations
Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. It is the most expensive healthcare condition to treat in United States and has a mortality rate of nearly 30%. It is widely known that exaggerated inflammation and imbalance between sympathetic and parasympathetic arms of the autonomic …

cytokines
resuscitation
systolic blood pressure
sepsis
severe sepsis
  • 0 views
  • 26 Jan, 2021
  • 1 location
Pudendal Nerve Mapping Towards Improved Neuromodulation for Urinary Retention

This study is to map the pudendal nerve. In this study the researchers will examine subjects who are already receiving an implanted stimulator at their pudendal nerve as part of their normal clinical care.

  • 0 views
  • 19 Nov, 2021
  • 1 location