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Found 218 clinical trials
Featured trial
Parkinson Progression Marker Initiative Online (PPMI Online)

Parkinson Progression Marker Initiative Online (PPMI online) is part of the broader Parkinson’s Progression Marker Initiative aimed at better understanding who gets Parkinson’s disease and why. PPMI online is a study collecting participant reported demographic and health information online from people with and without Parkinson’s disease. Once in the study, …

Accepts healthy volunteers
Online studies
  • 96 views
  • 30 Mar, 2022
  • 1 location
  • Online study
Featured trial
Use of a Non-Invasive Brainstem Neuromodulation Device to Improve Neurovascular Status in Parkinson's Disease

This study is a single-site, double-blinded, randomized clinical trial designed to elucidate mechanism(s) of action for symptomatic benefits observed in Parkinson's disease (PD)

motor symptoms
dopamine
  • 17 views
  • 06 Jun, 2022
  • 1 location
CPNS Pilot Study: Evaluation of Safety and Performance of the Cardiac Pulmonary Nerve Stimulation (CPNS) System in Patients With ADHF

The CPNS Pilot Study: An evaluation of the safety and performance of the Cardionomic Cardiac Pulmonary Nerve Stimulation (CPNS) system in patients with acute decompensated heart failure.

  • 1 views
  • 10 May, 2022
  • 14 locations
Neuromodulation for Dysphoria

This is an open label prospective pilot study of two neuromodulation interventions for patients suffering from dysphoria. Dysphoria is a transdiagnostic symptom of unease or dissatisfaction

  • 0 views
  • 10 Dec, 2021
  • 1 location
Non-invasive Vagus Nerve Stimulation in Patients Undergoing Electrophysiological Study (VNS-EPS)

The Non-invasive Vagus Nerve Stimulation in Patients Undergoing Electrophysiological Study is a single center, pilot, prospective study that aims at evaluating the effects of auricular vagus nerve stimulation (aVNS) on the human cardiac conduction system.

  • 0 views
  • 05 Jul, 2022
  • 1 location
Thoracic Neuromodulation for Diabetic Gastroparesis (TNM-DGp)

greater splanchnic nerve, innervating the foregut. Neuromodulation of the thoracic spinal nerves should improve diabetic gastroparesis symptoms and restore quality of life by improving neuropathy and

  • 0 views
  • 22 Jul, 2022
  • 1 location
Personalized Therapeutic Neuromodulation for Anhedonic Depression

This study will investigate the anti-anhedonic efficacy of a novel neurostimulation strategy termed accelerated intermittent theta burst stimulation (aiTBS) in participants with treatment resistant depression (TRD) or BD. aiTBS is a novel application of repetitive transcranial magnetic stimulation (TMS), that induces remission in 90% of individuals with severe, treatment resistant …

  • 0 views
  • 19 Jun, 2022
  • 1 location
Augmenting Standard-of-care Treatment of Plaque Psoriasis by Neuromodulation

The human body responds to inflammation, such as psoriatic skin lesions, by activating the cholinergic anti-inflammatory pathway. In patients with plaque psoriasis, this pathway is not sufficient to clear the skin lesions. Importantly, the vagus nerve, that is part of the anti-inflammatory pathway, also innervates the ear where it can …

  • 0 views
  • 12 May, 2022
  • 1 location
Imaging Brain Fluids During Breathing

This study will perform magnetic resonance imaging (MRI) measurements of hemodynamics and cerebrospinal fluid flow across breathing tasks and during breath-locked neuromodulation.

Accepts healthy volunteers
  • 0 views
  • 05 Apr, 2022
  • 1 location
Understanding the Neural Mechanisms Behind tDCS

The aim of the study is to investigate the neural mechanisms underpinning transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique in which a direct current is

Accepts healthy volunteers
  • 0 views
  • 09 Dec, 2021
  • 1 location