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Found 400 clinical trials
Featured trial
Protective Role of Pre-/ Post-biotics on Gut Inflammation, Dysbiosis, and Life Quality in Rett Syndrome (Biotics_RTT) (Biotics_RTT)

The study will examine the potential efficacy and safety of two pre- and post-biotics on markers for gut inflammation and intestinal microbiota ecology in patients with Rett syndrome. Moreover, this trial will search for possible effects on epileptogenesis and quality of life.

seizure
  • 2 views
  • 11 Jul, 2022
  • 1 location
Featured trial
Clinical Study for Treatment-naïve IOPD Babies to Evaluate Efficacy and Safety of ERT With Avalglucosidase Alfa (Baby-COMET)  

This is a single group, treatment, Phase 3, open-label study to assess efficacy, safety, pharmacokinetic (PK), pharmacodynamics (PD) of avalglucosidase alfa in treatment-naïve male and female participants with IOPD. Study details include: Study duration: Screening - up to 4 weeks; Primary Analysis Period (PAP) - 52 weeks; Extended Treatment Period …

replacement therapy
deficiency
  • 8 views
  • 31 Jan, 2023
  • 3 locations
Featured trial
Evaluate the Safety and Tolerability of Atogepant 10mg, 30 mg and 60 mg Once a Day for the Prevention of Migraine in Participants With Episodic Migraine

To evaluate the safety and tolerability of atogepant 30 mg and 60 mg once a day for the prevention of migraine in participants with episodic migraine.  

  • 133 views
  • 22 Feb, 2019
  • 1 location
Featured trial
A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment

This study will evaluate the safety, tolerability, and potential effects on cognition of GRF6021, a plasma-derived product, administered as an intravenous (IV) infusion, to subjects with Parkinson's disease and cognitive impairment.  

dementia
cognitive impairment
movement disorder
  • 151 views
  • 24 Jan, 2020
  • 1 location
Featured trial
Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Children and Adolescents >6 to

The main purpose of this study is to learn whether the study drug, rimegepant, is well tolerated and safe for the prevention of migraine compared to placebo in children and adolescents between the ages of 6 and 17 years. Enrollment starts with the 12 to 17 year old group. The …

  • 0 views
  • 19 Jan, 2023
  • 1 location
Featured trial
University of Michigan Memory and Aging Project

This study is interested in the symptoms that are associated with neurological disorders. This study asks: What symptoms develop during aging in people with neurological disorders? This

neurological disorder
Accepts healthy volunteers
  • 142 views
  • 24 Jan, 2022
  • 1 location
Featured trial
Living with Multiple Sclerosis? Enrolling for a 96-week, non-placebo, comparative trial.

Living with Multiple Sclerosis? Enrolling for a 96-week, non-placebo, comparative trial.

  • 428 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Advanced Non-Small Cell Lung Cancer

Advanced Non-Small Cell Lung Cancer

  • 138 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A Phase 3 Randomized, Double-Blind, Placebo-Controlled Multicenter Study Of Study Medicine On Peripheral Nerve Function In Patients With Osteoarthritis

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Multicenter Study Of Study Medicine On Peripheral Nerve Function In Patients With Osteoarthritis

  • 483 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Efficacy and Safety of Eslicarbazepine Acetate as adjunctive Therapy for refractory partial seizures in a double blind, randomized, placebo-controlled, parallel-group multicenter clinical trial

Efficacy and Safety of Eslicarbazepine Acetate as adjunctive Therapy for refractory partial seizures in a double blind, randomized, placebo-controlled, parallel-group multicenter clinical trial

  • 62 views
  • 08 Nov, 2020
  • 1 location