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Found 465 clinical trials
CASCADE: CAnnabidiol Study in Children With Autism Spectrum DisordEr (CASCADE)

This is a randomized, placebo-controlled study but all study participants will receive the active study medication at some point during the study for at least 12 weeks, and some children with receive CBD for the entire study.

  • 0 views
  • 22 Mar, 2022
  • 1 location
Pediatric Massage for Children With Autism Spectrum Disorder

This study was designed as a randomized controlled clinical trial of pediatric massage for children with Autism Spectrum Disorder (ASD). 72 ASD children will be recruited and randomly divided into two groups: the treatment group (pediatric massage + usual care, n=36) and the control group (usual care/waitlist group, n=36).30 healty …

  • 0 views
  • 08 Oct, 2021
  • 2 locations
Home-Based tDCS in Children With ADHD: A Randomized Sham-Controlled tDCS and fNIRS Study

The purpose of this study is to investigate the efficacy of twenty daily sessions of home-based tDCS over the left DLPFC, right IFG on attention and response inhibition in children with ADHD. Investigators hypothesize that multiple sessions of tDCS will induce a greater and long-term effect on attentional and/or inhibitory …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Effect of ESDM and PCIT-A in Autism Spectrum Disorder

Children with ASD often show disruptive behaviors. However, interventions that were specifically designed to improve these symptoms have not been sufficiently investigated, especially in children with level 1 to level 3 ASD. PCIT has large effects on externalizing behavior problems in children with disruptive behavior disorders. Recently PCIT was adapted …

  • 0 views
  • 15 Feb, 2021
  • 1 location
Effect of a Wide Spectrum Nutritional Supplement on Mitochondrial Function in Children With Autism Spectrum Disorder

The objective of this study is to evaluate the metabolic effects of a comprehensive wide-spectrum supplement for children with ASD to determine whether it physiologically targets mitochondrial pathways known to be abnormal in children with ASD.The intervention is a commonly used wide-spectrum nutritional supplement, which is theoretically designed to normalize …

pervasive developmental disorder
autism
  • 28 views
  • 25 Apr, 2022
  • 1 location
Treatment of Social and Language Deficits With Leucovorin for Young Children With Autism

The primary objective of this study is to evaluate the cognitive and behavioral effects of liquid leucovorin calcium on young children with autism spectrum disorder (ASD) and determine whether it improves social communication as well as the core and associated symptoms of ASD. The investigators will enroll 80 children across …

  • 12 views
  • 19 Mar, 2021
  • 2 locations
Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium

The primary objective of this study is to evaluate the cognitive and behavioral effects of liquid leucovorin calcium on young children with autism spectrum disorder (ASD) and determine whether it improves language as well as the core and associated symptoms of ASD. The investigators will enroll 80 children across two …

  • 0 views
  • 20 Mar, 2021
  • 2 locations
Leucovorin for the Treatment of Language Impairment in Children With Autism Spectrum Disorder

The purpose of this study is to determine the effectiveness of folinic acid in the treatment of language problems in children with autism spectrum disorder. Folinic acid, also known as leucovorin, is approved by the U.S. Food and Drug Administration (FDA) to decrease side effects during cancer chemotherapy. Folinic acid …

psychiatric disorder
leucovorin
language disorder
autism
pervasive developmental disorder
  • 222 views
  • 22 Mar, 2022
  • 3 locations
Testing a Novel Parenting Intervention for Children With Autism

This study will investigate the acceptability and preliminary effectiveness of training parents to use a structured communication intervention that is aimed towards helping children with autism spectrum disorder (ASD). This intervention has demonstrated benefits for non-autistic children in known areas of difficulty found with autistic individuals. There are currently few …

  • 0 views
  • 04 Feb, 2021
  • 1 location
Brain Tissue Integrity and Autonomic Function Alterations in Childhood OSA and ADHD and After Adenotonsillectomy.

Obstructive sleep apnea (OSA) and attention-deficit/hyperactivity disorder (ADHD) are two common, severe disorders in children. Unfortunately, pediatric OSA is closely associated with ADHD, and both diseases can cause cognitive impairment, behavior problems, and low academic performance. OSA can damage the brain and induce autonomic dysfunction, and then cause cognitive, behavioral, …

  • 0 views
  • 05 Feb, 2021
  • 1 location