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Found 432 clinical trials
Pharmacogenetic Supported Prescribing in Kids

Implementation of pharmacogenetic testing for children and adolescents aged 7-17 who are starting or changing psychiatric medication.

  • 6 views
  • 23 Mar, 2021
  • 1 location
Developmental Dyslexia and Remediation Methods

At least, three theoretical frameworks are currently involved in therapeutic research in developmental dyslexia. Each theoretical framework relies on the type of underlying cognitive processes that is viewed as impaired: 1) phonological processing, 2) cross modal integration, 3) visual attention processing. In this controlled and randomized study, three types of …

developmental dyslexia
rehabilitation treatment
  • 158 views
  • 26 Jul, 2021
  • 2 locations
Tolerability and Efficacy of L-Serine in Patients With GRIN-related Encephalopathy

GRIN-related disorders encompass a new group of Inborn Errors of Metabolism according to the recent nosology published by Ferreira et al (Genet Med, 2019). These rare conditions represent a subtype of paediatric encephalopathies leading to intellectual disability, hypotonia, communication deficits and motor impairment (Orphanet entries: 178469, 289266, 101685, for GRIN1, …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Prenatal Iodine Supplementation and Early Childhood Neurodevelopment

A randomized controlled trial to determine the effect of reducing iodine from vitamin and mineral supplements for pregnant women who have adequate iodine intakes (>165 g/d from food alone) on cognitive development of children at 24 months of age.

  • 0 views
  • 07 Aug, 2021
  • 1 location
Early Screening of Autism Spectrum Disorder in General and Pediatric Practices

pediatricians), the third line is constituted by expert teem in specialized hospital centers for neurodevelopmental disorders diagnostic. This organization is, for now, not efficient. First lines

neurodevelopmental disorder
chat
csbs
pervasive developmental disorder
autism
  • 42 views
  • 15 Aug, 2021
  • 1 location
A Treatment Study Protocol for Participants 1-45 Years With Acute Lymphoblastic Leukaemia

ALLTogether collects the experience of previously successful treatment of children and young adults, with ALL from a number of well-renowned study groups into a new master protocol, which is both a comprehensive system for stratification and treatment of ALL in this age-group as well as the basis for several randomised …

dexamethasone
doxorubicin
inotuzumab
imatinib
vincristine
  • 28 views
  • 27 Jan, 2021
  • 102 locations
Dance for Children With Neurodevelopmental Disorders

classes on children with neurodevelopmental disorders (ages 4-17) and their caregivers. Participants will complete a set of surveys and assessments designed to measure the above metrics (labeled 1, 2

  • 7 views
  • 05 Mar, 2021
  • 1 location
Novel Epigenetic Biomarker for Prematurity Related Neurodevelopmental Disorders in Childhood

Preterms are early exposed to a stressful environment (i.e. excessive sensory stimulation and paucity of parental contact) with subsequent detrimental effects on brain maturation and neurodevelopmental outcomes. In contrast, early interventions seem to reduce stress exposure and promote neurodevelopment. The brain functional plasticity in response to environmental experiences can be …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Phenylbutyrate for STXBP1 Encephalopathy and SLC6A1 Neurodevelopmental Disorder

gene's protein to not work properly. SLC6A1 neurodevelopmental disorder is characterized by developmental delay and often epilepsy. It occurs when one copy of the SLC6A1 gene has a mutation that

  • 11 views
  • 26 Aug, 2021
  • 2 locations
Supporting Parenting at Home: Empowering Rehabilitation Through Engagement (SPHERE)

Infants with Neurodevelopmental Disabilities (ND) show emotional, cognitive and socio-interactive dysregulation dramatically impacting on caregiving behavior. Early family-centered rehabilitation interventions are effective in promoting better infant outcomes and in optimizing healthcare systems economic return in the long-term. The Video Feedback intervention (VFI) is effective in promoting sensitive parenting and supporting …

  • 0 views
  • 16 Apr, 2021
  • 1 location