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Found 1523 clinical trials
Study to Assess the Efficacy of XPro™ in Patients With Mild Alzheimer's Disease With Biomarkers of Inflammation (MINDFuL)

The purpose of this study is to measure cognitive and biological biomarkers in subcutaneously administered XPro™ or placebo in patients with mild ADi.

cognitive assessment
mild dementia
alzheimer's disease
amyloid
dementia
  • 0 views
  • 04 Oct, 2022
  • 1 location
New Magnetic Resonance Imaging Biomarkers in Amyotrophic Lateral Sclerosis (IRM-SLA)

Amyotrophic lateral sclerosis (ALS) is a disabling and rapidly progressive neurodegenerative disorder. There is no treatment that significantly slows progression. Our project aims to find new

primary lateral sclerosis
Accepts healthy volunteers
spinal cord
  • 0 views
  • 04 Oct, 2022
  • 1 location
tDCS Intervention in Primary Progressive Aphasia

Primary progressive aphasia (PPA) is a neurodegenerative disease that affects first and foremost language abilities. Mild cognitive impairment (MCI) is slowly progressive decline in a single

aphasia
alzheimer's disease
transcranial direct current stimulation
neurodegenerative disorders
neuropsychological assessment
  • 7 views
  • 15 Jul, 2022
  • 1 location
BoMI for Muscle Control

People with spinal cord injury (SCI), stroke and other neurodegenerative disorders can follow two pathways for regaining independence and quality of life. One is through clinical interventions

  • 0 views
  • 27 Jan, 2021
  • 1 location
An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease

The goal of this Phase 2 Open-Label Extension (OLE) is to evaluate long-term safety, tolerability, and efficacy of XPro1595 on measures of cognition, function and brain quality in individuals with mild Alzheimer's Disease or MCI with biomarkers of inflammation.

alzheimer's disease
cognitive assessment
  • 0 views
  • 07 Oct, 2022
  • 1 location
Trial of Dronabinol Adjunctive Treatment of Agitation in Alzheimer's Disease (THC-AD)

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease of aging. Neuropsychiatric symptoms (NPS) in AD are a major cause of burden to patients, caregivers, and society and are

psychiatric disorder
agitation
neuropsychiatric symptoms
alzheimer's disease
neurodegenerative disorders
  • 80 views
  • 04 Oct, 2022
  • 3 locations
The Effects of a Multimodal Approach for the Treatment of Primary Progressive Aphasia (ACROSS)

Primary Progressive Aphasia (PPA) is an untreatable neurodegenerative disorder that disrupts language functions. Available therapies are mainly symptomatic and recently attention has been gained

dementia, frontotemporal
  • 0 views
  • 24 Feb, 2022
  • 1 location
Validation of Serum Neurofilament Light Chain as a Biomarker to Differentiate Cognitive Impairment From Neurodegenerative or Psychiatric Diseases (Nfl_COG)

concentrations of neurofilaments in CSF of psychiatric patients compared to neurodegenerative diseases. The main objective of this study is to validate the plasma assay of neurofilament light chain as a

bipolar disorder
alzheimer's disease
schizophrenia
cognitive impairment
  • 0 views
  • 21 Oct, 2022
  • 2 locations
Neurologic Stem Cell Treatment Study (NEST)

This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will provide improvement in neurologic function for patients with certain neurologic conditions. …

nervous
  • 430 views
  • 04 Oct, 2022
  • 3 locations
Patient-Centered NeuroRehabilitation (PCN) (PCN)

As individuals grow older, a number of factors can reduce our cognitive (or thinking) abilities such as "normal" aging, neurodegenerative diseases, and cardiovascular disease. This study will

cognitive rehabilitation
Accepts healthy volunteers
transcranial direct current stimulation
neurodegenerative disorders
cognitive impairment
  • 4 views
  • 27 Jan, 2022
  • 1 location