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Found 6 clinical trials
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Efficacy of Olanzapine Netupitant and Palonosetron in Controlling Nausea and Vomiting Associated With Highly Emetogenic Chemotherapy in Patients With Breast Cancer

This is a longitudinal, one arm, prospective phase II study, designed to evaluate the efficacy of Olanzapine Netupitant and Palonosetron in the controll of nausea and vomiting induced by highly

  • 0 views
  • 04 Apr, 2021
  • 1 location
None
Netupitant/Palonosetron Hydrochloride and Dexamethasone With or Without Prochlorperazine or Olanzapine in Improving Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer

This randomized phase III trial studies how well netupitant/palonosetron hydrochloride and dexamethasone with prochlorperazine or olanzapine work compared to netupitant/palonosetron

herceptin
biomarker analysis
trastuzumab
cyclophosphamide
cancer
  • 6 views
  • 11 Nov, 2021
  • 16 locations
None
Oral Akynzeo vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk)

MyRisk: Efficacy and safety evaluation of oral Akynzeo in patients receiving MEC at high risk of developing CINV based on a prediction tool. A multinational and multicenter study. Antiemetic guidelines recommendations are based on the emetogenic potential of the chemotherapy. Chemotherapy (CT) agents are divided in Highly, Moderately, Low and …

  • 3 views
  • 25 Sep, 2021
  • 5 locations
None
Safety and Antiemetic Efficacy of Akynzeo Plus Dexamethasone During Radiotherapy and Concomitant Weekly Cisplatin

This is a multicentre, single-arm, phase II study to investigate the safety and antiemetic efficacy of Akynzeo (a fixed dose combination of palonosetron and netupitant) plus dexamethasone in

absolute neutrophil count
antiemetics
akynzeo
cancer
netupitant
  • 7 views
  • 24 Jan, 2021
  • 1 location
None
AKY15-HK-301_NEPA Study

response to conditions that affect the gut and the vomiting center, which is an area in the brain. Netupitant and palonosetron are drugs that are thought to block the activation of certain types of

adriamycin
cyclophosphamide
adjuvant chemotherapy
immunostimulant
cancer treatment
  • 0 views
  • 07 Aug, 2021
  • 1 location
None
Comparing the Current Hydration Regimen for the ABC02 Chemotherapy Regimen Versus a Shorter Hydration

This is an open label study for any patients with a bile duct cancer or gallbladder cancer, who will be treated with gemcitabine and cisplatin chemotherapy (the ABC02 regime). Patients recruited onto this study will have a reduction of their hydration time and be given Akynzeo as an anti-sickness drug, …

cholangiocarcinoma
cancer
gemcitabine
akynzeo
carcinoma
  • 4 views
  • 13 Mar, 2021
  • 1 location