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Found 5850 clinical trials
Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex Neuroplasticity (LIFUS-Pharma)

resolution than other brain stimulation tools. Its use as a potential clinical tool for treatment of neurological disorders is reliant on an understanding of its mechanisms of action. Although it has been

Accepts healthy volunteers
  • 0 views
  • 08 Jun, 2022
  • 1 location
A Phase I Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy Study of Oral Monepantel in Individuals With Motor Neurone Disease

Amyotrophic lateral sclerosis/ Motor Neurone Disease (ALS/MND) is a rare and invariably fatal neurological disease. ALS/MND has a terribly high burden on patients, family and carers, and carries

  • 0 views
  • 28 Oct, 2022
  • 2 locations
The Role of Meningeal Lymphatic Vessels in the Absorption of Chronic Subdural Hematoma and Its Injury Mechanism

such as Alzheimer's disease (AD), traumatic brain injury (TBI), and subarachnoid hemorrhage (SAH). This phenomenon suggests that mLVs play an important role in central nervous system diseases.

Accepts healthy volunteers
  • 0 views
  • 07 Jul, 2022
  • 1 location
Radiofrequency Perineural Injection Idiopathic Carpal Tunnel Syndrome

Aim of the study The aim of the study is to evaluate the role of pulsed radiofrequency versus platelet rich plasma injection in treatment of idiopathic mild to moderate carpal tunnel syndrome Patients will be classified into three equal groups using randomized closed envelop method into three groups. Control Group …

nerve conduction
bupivacaine
conservative management
ultrasound guidance
paresthesia
  • 1 views
  • 06 Oct, 2021
  • 1 location
Research on an Electronic APP to Improve the Oral Biomechanics of Hong Kong Elderly (HOE)

Hong Kong and Japan are similar in terms of facing the super-ageing society. Maintaining oral function in elderly is particularly important because it affects social, physical and mental health to the people and to the society. By using technology seems to be one of the solutions in dealing with this. …

Accepts healthy volunteers
  • 0 views
  • 29 Oct, 2022
  • 1 location
Brain-Computer Interfaces in Laryngeal Dystonia

The researchers will develop and evaluate the use of adaptive closed-loop brain-computer interface therapeutic intervention in laryngeal dystonia.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Safety and Efficacy of Esmketamine Versus Dexmedetomidine

A comparative study on the safety and efficacy of esmketamine versus Dexmedetomidine during drug induced sleep endoscopy in children with positional obstructive sleep apnea: A consort-prospective, randomized, controlled clinical trial

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Brain State-dependent Stimulation to Improve Movement (BrainSTIM)

Repetitive transcranial magnetic stimulation (rTMS) is a powerful tool to non-invasively modulate brain circuits, brain plasticity, and behavior. This proposal will test the hypothesis that controlling behavioral state during focal multi-day rTMS of a brain region involved in grasping movements will enhance the functional specificity of the neuromodulation action among …

Accepts healthy volunteers
  • 2 views
  • 06 Apr, 2022
  • 1 location
A Phase 1a/1b Trial of Intrathecal Deferoxamine for Leptomeningeal Metastases

The researchers are doing this study to find out whether deferoxamine (DFO) given intrathecally (directly into the CSF) is a safe treatment for people with leptomeningeal metastasis from solid tumor cancer. The researchers will test different doses of DFO to find the highest dose that causes few or mild side …

  • 0 views
  • 16 Oct, 2022
  • 7 locations
Bloodletting Puncture in the Treatment of Acute Ischemic Stroke

The bloodletting puncture is an external treatment for acute ischemic stroke by releasing an appropriate amount of blood with a three-edged needle at specific points on the patient's body. As a special treatment for acute ischemic stroke, it has been used clinically in hospitals of traditional Chinese medicine in China …

  • 0 views
  • 06 May, 2022
  • 1 location