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Found 1244 clinical trials
Featured trial
Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations (FIGHT-209)

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblatoma (GBM) or other primary CNS tumors with an activating FGFR1-3 mutation or fusion/rearrangement. This study consists of 3 cohorts, Cohorts A, B, and C, and will enroll approximately 82, 82, and 25 participants into each cohort, respectively. …

  • 0 views
  • 25 May, 2022
  • 1 location
Featured trial
An MRI-Study to Characterize Cerebrospinal Fluid Geometry and Dynamics in Individuals with Rett Syndrome

at the CNS target areas.Delivery of drugs to the CSF to help treat central nervous system diseases has shown promising pre-clinical and clinical results. However, at present, the

  • 0 views
  • 15 Feb, 2022
  • 1 location
Featured trial
GAIN: GingipAIN Inhibitor for Treatment of Alzheimer's Disease

bacteria and its toxins in their central nervous system. This clinical trial evaluates whether the investigational drug COR388 is safe and can slow or stop the progression of Alzheimer’s Disease

senile plaques
  • 153 views
  • 08 Dec, 2020
  • 1 location
Featured trial
Clinical Validation of At-Home Methods of Sleep Assessment in Rett Syndrome

measure Blood Volume Pulse, sympathetic nervous system arousal, local skin temperature, as well as hand movements.Families can choose to participate in a second optional component

  • 0 views
  • 15 Feb, 2022
  • 1 location
Featured trial
A Research Study for Pentalogy of Cantrell

This study will collect blood, urine, and other tissue samples from patients with Pentalogy of Cantrell (POC) and other inherited diseases that may involve mutations in non-muscle myosin II-B heavy chain (MYH10). We will also collect samples from the relatives of affected individuals. POC is a very rare disorder in …

nervous system disease
congenital disorders
nervous system disorders
  • 19 views
  • 22 Dec, 2020
  • 1 location
Featured trial
ACNS1123: Phase 2 Trial of Response-Based Radiation Therapy for Patients With Localized Central Nervous System Germ Cell Tumors (CNS GCT)

ACNS1123: Phase 2 Trial of Response-Based Radiation Therapy for Patients With Localized Central Nervous System Germ Cell Tumors (CNS GCT)

  • 176 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Metastatic Colorectal Cancer with wild-type KRAS tumors.

Metastatic Colorectal Cancer with wild-type KRAS tumors.

  • 266 views
  • 25 Mar, 2021
  • 1 location
Featured trial
Advanced Non-Small Cell Lung Cancer

Advanced Non-Small Cell Lung Cancer

  • 138 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Worried? Fearful?

Worried? Fearful?

  • 5461 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Phase 3, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Investigational Product in Patients With Systemic Lupus Erythematosus (SLE)

A Phase 3, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Investigational Product in Patients With Systemic Lupus Erythematosus (SLE)

  • 974 views
  • 08 Nov, 2020
  • 1 location