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Found 36 clinical trials
Post Approval Study for Treatment of Drug-resistant Adult Primary FSGS Using the LIPOSORBER LA-15 System

This multicenter, prospective, single-arm clinical study will evaluate the probable benefit and safety of the LIPOSORBER LA-15 System for the treatment of adult patients with nephrotic syndrome

corticosteroids
calcineurin inhibitors
kidney transplant
primary focal segmental glomerulosclerosis
plasma cholesterol
  • 93 views
  • 05 May, 2021
  • 10 locations
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

To evaluate the safety, efficacy and tolerability of sparsentan oral suspension and assess changes in proteinuria after once-daily dosing over the 108-week treatment period.

corticosteroids
proteinuria
kidney biopsy
total protein
mammogram
  • 0 views
  • 13 Jan, 2022
  • 5 locations
Rescue Therapy With the Human Anti-CD38 Antibody MOR202 (Felzartamab) in Patients With Membranous Nephropathy Who Failed Anti-CD20 Target Therapy

Membranous nephropathy (MN) - the leading cause of nephrotic syndrome (NS) in adults - is an immune-mediated disease that results from the deposition of immunoglobulins and complement components

cyclosporin
adrenaline
rituximab
monoclonal antibodies
proteinuria
  • 0 views
  • 22 Dec, 2021
  • 2 locations
PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

This is a phase III, multicenter, randomized, open label, clinical trial to test that hypothesis that plasmapheresis plus rituximab prior to kidney transplantation can prevent recurrent FSGS in children and adults.

obesity
kidney transplant
primary focal segmental glomerulosclerosis
minimal change disease
hepatitis c
  • 83 views
  • 01 Dec, 2021
  • 14 locations
INSIGHT (Insight Into Nephrotic Syndrome)

INSIGHT is a longitudinal study of childhood nephrotic syndrome to determine genetic, serologic and environmental factors contributing to nephrotic syndrome and disease progression.

  • 148 views
  • 21 Mar, 2021
  • 5 locations
Super Chinese Nephrotic Syndrome Registration System (SUCCESS)

The investigators are registering all nephrotic syndrome (NS) patients regardless of the primary causes and developing a NS database in China. Patients will be followed-up and both baseline and

renal function
  • 0 views
  • 26 Jan, 2021
  • 1 location
Non-invasive Assessment of Mechano-chemical Properties of Urine Proteins by Hybrid Brillouin-Raman Spectroscopy

The proteinuria is widely recognized as a marker of kidney disease severity, as well as the predictor of renal function decline, cardiovascular outcomes, and all-cause mortality. However, the severity of kidney disease progression and these outcomes differs among patients with various amount of proteinuria. The potential mechanism underlining this disparity …

renal function
glomerulonephritis
proteinuria
nephropathy
  • 0 views
  • 11 Mar, 2021
  • 1 location
From Immune System Damage to Podocyte Cell Damage: Prospective Database and Biological Collection of Patients (Children and Adults) With MGLS and HSFP

Idiopathic Nephrotic Syndrome (INS) is a kidney disease characterized by massive proteinuria and hypoalbuminemia. It includes two anatomopathological entities: nephrotic syndrome with minimal

corticosteroids
hypoalbuminemia
proteinuria
kidney biopsy
immunosuppressive agents
  • 0 views
  • 25 Jan, 2021
  • 2 locations
Nephrotic Syndrome Study Network

establishment of a Nephrotic Syndrome (NS) Rare Diseases Clinical Research Consortium. Through this consortium the investigators hope to understand the fundamental biology of these rare diseases and aim

end stage renal disease
rare diseases
edema
kidney biopsy
swelling
  • 363 views
  • 15 Jan, 2022
  • 35 locations
Immune System Related Kidney Disease

Kidney diseases related to the immune system include, nephrotic syndrome, glomerulonephritis, membranous nephropathy, lupus nephritis, and nephritis associated with connective tissue disorders

membranous nephropathy
nephropathy
autoimmune diseases
glomerulonephritis
nephritis
  • 218 views
  • 22 Jan, 2022
  • 1 location