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Found 36 clinical trials
An Open-Label Long-term Study of GFB-887 in Patients With Glomerular Kidney Diseases

This is an open-label Phase 2 study evaluating the long term safety and tolerability of GFB-887 in patients with focal segmental glomerulosclerosis (FSGS), and treatment-resistant minimal change disease (TR-MCD)

segmental glomerulosclerosis
proteinuria
glomerulosclerosis
minimal change disease
focal segmental glomerulosclerosis
  • 0 views
  • 23 Sep, 2021
  • 8 locations
Efficacy of Rituximab in Comparison to Continued Corticosteroid Treatment in Idiopathic Nephrotic Syndrome

This will be an open-label, randomized controlled trial which compares continued treatment with high dose prednisone (standard therapy) to treatment with rituximab in patients with minimal change disease or focal segmental glomerulosclerosis unresponsive to 8 weeks of high dose prednisone . patients either receive 2 doses of Rituximab 375 mg/m2 …

corticosteroids
minimal change disease
prednisone
rituximab
proteinuria
  • 52 views
  • 22 Jan, 2021
  • 1 location
Rituximab Versus Mycophenolate Mofetil in Children With Steroid-dependent Idiopathic Nephrotic Syndrome.

maintains drug-free disease remission in patients with steroid-dependent nephrotic syndrome for 12-24 months and verify its superiority vs. mycophenolate mofetil (1,200 mg/m2 orally in 2 daily doses). The

  • 0 views
  • 13 May, 2021
  • 1 location
Efficacy and Safety of Rituximab in the First Episode of Pediatric Idiopathic Nephrotic Syndrome

The main objective is to demonstrate, from the initial episode of nephrotic syndrome (NS) in children with standard prednisolone treatment, once complete remission has occurred, that the use of

  • 0 views
  • 13 Dec, 2021
  • 11 locations
Belimumab With Rituximab for Primary Membranous Nephropathy

participants with PM. Background Primary membranous nephropathy (MN) is among the most common causes of nephrotic syndrome in adults. MN affects individuals of all ages

mammogram
monoclonal antibody
monoclonal antibodies
arthritis
rituximab
  • 296 views
  • 12 Sep, 2021
  • 11 locations
Effect of Daily Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Proteinuria in Pediatric Patients With Idiopathic Nephrotic Syndrome

This study evaluates the impact of transcutaneous auricular Vagus Nerve stimulation (taVNS) therapy on the incidence of nephrotic syndrome relapses in children with idiopathic nephrotic syndrome

  • 0 views
  • 06 Sep, 2021
  • 1 location
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Background Membranous nephropathy is associated with damage to the walls of the glomeruli, the small blood vessels in the kidneys that filter waste products from the blood. This damage causes leakage of blood proteins into the urine and is associated with low blood protein levels, high blood cholesterol values, and …

intravenous infusions
blood proteins
edema
cyclosporin
mammogram
  • 236 views
  • 20 Jan, 2022
  • 2 locations
A Study of TRPC5 Channel Inhibitor in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease

This is a phase 2a study evaluating the safety and tolerability of multiple ascending doses of GFB-887 in patients with diabetic nephropathy (DN), focal segmental glomerulosclerosis (FSGS), and treatment-resistant minimal change disease (TR-MCD).

angiotensin converting enzyme
diabetic nephropathy
hba1c
mammogram
type 1 diabetes mellitus
  • 205 views
  • 21 Dec, 2021
  • 60 locations
Personalized Medicine for Membranous Nephropathy

Membranous Nephropathy with nephrotic syndrome and anti-PLA2R1 (phospholipase A2 receptor 1) antibodies GEMRITUX protocol: 6 months of symptomatic antihypertensive and

diuretics
remission
antihypertensive
protein creatinine ratio
rituximab
  • 0 views
  • 24 Jan, 2021
  • 24 locations
Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

common complication of nephrotic syndrome and found to bring about improvement not only with the dyslipidemic condition but the nephrotic condition (e.g, proteinuria and hypoproteinemia).

corticosteroids
low density lipoprotein
alternative therapies
kidney transplant
plasma cholesterol
  • 36 views
  • 07 May, 2021
  • 8 locations