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Found 40 clinical trials
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Long Term Tapering or Standard Steroids for Nephrotic Syndrome

Parallel group double blind randomised in patients with first episode corticosteroid sensitive nephrotic syndrome comparing time to relapse and adverse effects associated with a longer

corticosteroids
prednisolone
hypoalbuminemia
  • 9 views
  • 07 Nov, 2020
  • 1 location
None
Lymphocyte Markers As Predictors Of Responsiveness To Rituximab Among Patients With Idiopathic Nephrotic Syndrome

The purpose of this study is to investigate if lymphocyte markers predict response to rituximab among patients with idiopathic nephrotic syndrome

rituximab
steroid-resistant nephrotic syndrome
minimal change disease
  • 5 views
  • 23 Jan, 2021
  • 1 location
None
Furosemide Alone or Unexpectedly With Solution of Hypertonic Saline in Nephrotic Syndrome

The trial will test the hypothesis that hypertonic saline on top of standard diuretic treatment will help achieve adequate diuresis in patients with nephrotic syndrome.

diuretic treatment
hypoalbuminemia
proteinuria
  • 0 views
  • 16 Feb, 2021
  • 1 location
None
Study of Tacrolimus vs Mycophenolate Mofetil in Pediatric Patients With Nephrotic Syndrome

Primary nephrotic syndrome accounts for approximately 90% of the total number of nephrotic syndrome in childhood and it is the most common glomerular disease in children. Although treatment with

  • 0 views
  • 12 Jun, 2021
  • 12 locations
None
Comparison of Relapse Rate After 12 Weeks Verses 20 Weeks Steroid Therapy for the Management of First Episode of Steroid Sensitive Nephrotic Syndrome

All children from 1 to 8 years of age, diagnose with nephrotic syndrome for the first time will be divided into two groups. One group will be given steroids for 12 weeks and other group will

  • 0 views
  • 16 May, 2021
  • 1 location
None
A Clinical Study to Evaluate the Potential Role of ACTH Gel in Patients With Scleritis

ATLAS study is a clinical trial to evaluate the potential role of subcutaneous adrenocorticotropic hormone (ACTH) gel in the management of non-infectious scleritis. Specifically, the ATLAS Study aims to evaluate the safety, tolerability and effect of 2 different dose regimens of ACTH gel administered by subcutaneous (SC) injection in patients …

  • 1 views
  • 16 Aug, 2021
  • 5 locations
None
Amiloride in Nephrotic Syndrome

The AMILOR study compares treatment of edema in nephrotic syndrome with Amiloride vs. Furosemide.

proteinuria
  • 0 views
  • 20 Oct, 2021
  • 1 location
None
Causes and Prevention of Thromboembolic Disease in Nephrotic Syndrome

The study aims to describe the biochemical coagulation profile and investigate the effect of Low molecular weight heparin and Apixaban on this profile in patients with nephrotic syndrome.

  • 0 views
  • 30 Apr, 2021
  • 1 location
None
Active Vitamin D And Reduced Dose Prednisolone for Treatment in Minimal Change Nephropathy

Traditionally MCN is treated with a high dose of prednisolone, which induces remission in 60-90% of patients. Prednisolone treatment contains numerous side effects and the current dose is empiric. Given the lack of efficacy evidence and the risk associated with the currently accepted treatment regimen there is a need to …

treatment regimen
active vitamin d
nephropathy
vitamin d
minimal change disease
  • 18 views
  • 04 Apr, 2021
  • 2 locations
None
A Prospective Multi-dose Study of Apixaban in Subjects With Nephrotic Syndrome

This phase I study is a single arm, multi-dose study that will evaluate steady-state apixaban pharmacokinetics (PK) and pharmacodynamics (PD) in subjects with Nephrotic Syndrome (NS) vs healthy

chronic kidney disease
apixaban
hypoalbuminemia
proteinuria
mammogram
  • 0 views
  • 03 Sep, 2021
  • 1 location