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Found 110 clinical trials
Rituximab and RASi in Patients With IgAN

A study to evaluate safety and activity in treatment of IgAN patients using Rituximab in combination with RASi(ACEI and/or ARB) compared with RASi.

rituximab
ras 2410
primary iga nephropathy
proteinuria
kidney biopsy
  • 0 views
  • 25 Jan, 2021
  • 1 location
Mesenchymal Stem Cells Transplantation for Refractory Systemic Lupus Erythematosus (SLE)

This study will explore a new approach to treat patients with a medical condition known as systemic lupus erythematosus (SLE) who have been resistant to previous treatments using a new population of cells with capability to restore a normal immune system that will no longer attack the body. The stated …

  • 30 views
  • 07 Nov, 2020
  • 1 location
ASA Patterns for Prevention of Preeclampsia in SLE Pregnancies

Preeclampsia is a serious maternal condition affecting up to 5% of pregnancies from the general population and up to 30% of lupus pregnancies. Aspirin (acetylsalicylic acid- ASA) has been shown to reduce the risk of preeclampsia, by half, in women at high risk. Therefore, it is recommended that health professionals …

aspirin
lupus
  • 11 views
  • 07 Mar, 2021
  • 2 locations
Anti-Viral Effects of Voclosporin in COVID-19 Positive Kidney Transplant Recipients

An open-label, 56 day, single-center, exploratory, proof-of-concept study of the anti-viral effect of voclosporin (VCS) with an extended safety follow-up, up to 1 year. Study population are adult KTRs with positive SARS-CoV-2 infection with mild to moderate symptoms. At study entry, subjects are on standard therapy of dual immunosuppressive treatment …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Safety Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies

The primary objective is to assess the safety and tolerability of TAB004 as monotherapy and in combination with toripalimab in subjects with selected advanced solid malignancies, including lymphoma, and to evaluate the recommended Phase 2 dose. The secondary objectives are to: 1) describe the pharmacokinetic (PK) profile of TAB004 monotherapy …

  • 0 views
  • 16 Apr, 2021
  • 11 locations
SVF (Adipose Tissue Derived MSC) Based Therapy for CKD.

To assess the safety of stromal vascular fraction (Autologous Non Expanded ADSC) injection to patients with Chronic Kidney Disease. To assess the efficacy of stromal vascular fraction (Autologous Non Expanded ADSC) injection to patients with Chronic Kidney Disease.

glomerular filtration rate
nephropathy
  • 6 views
  • 24 Jan, 2021
  • 1 location
Cyclophosphamide in Lupus Nephritis

Cyclophosphamide is widely used in the treatment of cancer and autoimmune diseases such as lupus nephritis. However, there is considerable variability in the response to cyclophosphamide

rituximab
autoimmune disease
cyclophosphamide treatment
nephritis
mycophenolate
  • 205 views
  • 07 Nov, 2020
  • 1 location
Anti-ficolin-3 Antibodies in Lupus Nephritis

anti-ficolin-3 antibodies and active nephritis in patients with SLE. However, the possible involvement of anti-ficolin-3 antibodies in the pathogenesis of SLE and particularly in lupus nephritis (LN

  • 9 views
  • 27 Jan, 2021
  • 1 location
Multicenter Registry of Pediatric Lupus Nephritis in China

This study is designed to evaluate the efficacy and safety of the current treatment option and outcome of pediatric lupus nephritis patients in China. Investigators will perform prospective

  • 0 views
  • 22 Jan, 2021
  • 1 location
High Quality Evidence of Chinese Lupus Nephritis (HELP)

The investigators are registering LN patients at recruited hospitals and developing a LN database in China. Patients will be follow-up every year, and both baseline and follow-up information will be entered into the registration system.

nephritis
  • 19 views
  • 26 Jan, 2021
  • 1 location