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Found 71 clinical trials
GRADE-SRM: Genomic Risk Assessment and Decisional Evaluation for Small Renal Masses (GRADE-SRM)

Purpose: The purpose of this study is to evaluate the role of renal mass biopsy on decision-making for patients presenting with clinical T1 kidney tumors. This study also incorporates integrated biomarker study to compare the genomic data obtained through biopsy tissue to genomic information from surgical data.

renal neoplasm
cancer
  • 0 views
  • 09 Apr, 2022
  • 1 location
Reduction of Allogenic Blood Transfusion in Locally Advanced Kidney Cancer

The Reduction of Allogenic Blood Transfusion in Locally Advanced Kidney Cancer Trial (RESTRICT). The primary objective is to reduce the number of units of allogenic blood transfusion in locally advanced kidney cancer ( cT2). Secondary objectives include reduction in perioperative complications, assessment of recurrence free-survival and improving overall survival.

nephrectomy
cancer
  • 0 views
  • 07 Aug, 2021
  • 3 locations
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

This phase II trial studies how well lenvatinib and pembrolizumab before surgery work in treating patients with kidney cancer that has spread from its original site of growth to nearby tissues or lymph nodes but has not spread to other places in the body (non-metastatic). Lenvatinib may stop the growth …

anticoagulants
pembrolizumab
neutrophil count
glomerular filtration rate
metastasis
  • 0 views
  • 22 Mar, 2022
  • 1 location
Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation Delivered With Proton Beam Irradiation

Participants are being asked to take part in this clinical trial, a type of research study, because the participants have a Wilms Tumor cancer. Primary Objectives To determine whether delivery of proton beam radiation to a conformal reduced target volume in the flank allows normal flank growth compared to the …

MRI
chemotherapeutic agents
cancer
tumor cells
metastasis
  • 0 views
  • 11 Sep, 2021
  • 1 location
SBRT With Combination Ipilimumab/Nivolumab for Metastatic Kidney Cancer (CYTOSHRINK)

This trial will evaluate the addition of cytoreductive stereotactic body radiation therapy (SBRT) to standard of care combination ipilimumab and nivolumab (I/N) versus I/N alone for the treatment of metastatic kidney cancer.

ipilimumab
nivolumab
metastasis
cancer
kidney cancer
  • 0 views
  • 23 Apr, 2022
  • 6 locations
Indo-cyanine Green (ICG) in Paediatric Oncology MIS

Indo-cyanine green (ICG) is a dye that has been used for a variety of adult and paediatric uses since 1956. Over the past few years, near infrared (NIRF) technology has been developed which allow is use as a fluorescence agent during surgery. It has been used increasingly in the field …

metastasis
cancer
  • 0 views
  • 19 Aug, 2021
  • 1 location
PET/MR Characterization of Renal Cell Carcinomas

Purpose: To evaluate the utility of simultaneous positron emission tomography (PET) and magnetic resonance imaging (MRI) in characterizing the molecular subtypes of clear cell renal cell carcinomas (ccRCC) to potentially inform prognosis and treatment decisions. Participants: Seventeen subjects diagnosed with clear-cell renal cell carcinoma (ccRCC) will be imaged in a …

nephrectomy
pet scan
cancer
carcinoma
  • 0 views
  • 03 Nov, 2021
  • 1 location
Non-Contrast Perfusion Using Arterial Spin Labeled MR Imaging for Assessment of Therapy Response in Metastatic Renal Cell Carcinoma

Magnetic Resonance Imaging (MRI) including Arterial Spin Labeling (ASL) will be performed before, during, and after the treatment, in a total of up to 6 MRI sessions until 7 months after the first session, or when progression is clinically indicated. Thereafter, patients will be followed through standard clinical examinations for …

metastatic renal cell carcinoma
tubal ligation
Accepts healthy volunteers
carcinoma
  • 0 views
  • 20 Apr, 2022
  • 1 location
Pembrolizumab With or Without Axitinib for Treatment of Locally Advanced or Metastatic Clear Cell Kidney Cancer in Patients Undergoing Surgery

This phase II trial studies how well pembrolizumab with or without standard of care axitinib works in treating patients with clear cell kidney cancer that has spread to nearby tissues or lymph nodes (locally advanced) or other places in the body (metastatic) who are undergoing surgery. Pembrolizumab is an antibody …

pet scan
axitinib
kidney cancer
anticoagulants
tyrosine
  • 0 views
  • 12 May, 2022
  • 1 location
Ketamine vs Lidocaine in Traumatic Rib Fractures

Rib fractures continue to be a common occurrence in trauma patients of all ages. Traumatic rib fractures can cause severe pain in patients and lead to shallow breathing and further complications such as the need for mechanical ventilation, hospital or ventilator associated pneumonia, atelectasis, and acute respiratory distress syndrome. Effective …

  • 0 views
  • 11 May, 2022
  • 1 location